Adam’s Journal
By now, we’ve seen the headlines about the outbreak of hantavirus aboard a cruise ship earlier this month. Is this something we need to worry about?
Dr. Scofield Prescribes
The hantavirus is what’s known as a zoonotic virus, meaning it originates in animals and can be spread to humans. For most hantavirus strains, this is as far as it goes. Even if a human catches the virus from rodent exposure – different species of the virus are carried by different rodents, and it most commonly spreads by breathing in particles of dried rodent droppings or urine – that’s where it ends.
However, there is an extremely rare strain of the virus that has the ability to spread from human to human. It’s known as the Andes virus, and it’s deadlier than most other forms of hantavirus. This is because the strain seems to affect the heart and lungs more than most other strains.
As with all forms of hantavirus, there are no targeted treatments or approved vaccines for the Andes virus. Symptoms can be treated with oxygen therapy and fluid replacement, but the Andes virus causes severe respiratory failure and has an estimated fatality rate of 35% to 50%.
Based on genetic sequencing that’s been performed on samples taken from several passengers on the cruise ship, it appears to be a strain quite similar to the Andes virus that caused the new outbreak.
In 2018, the Andes virus spread through a small town in Argentina, infecting 34 people, 11 of them fatally. An analysis found that the outbreak began when one person, infected from a rodent, attended a birthday party of about 100 people.
In the months that followed, three people infected at the party attended other social gatherings while ill and symptomatic. It was, researchers found, those interactions that drove every subsequent infection.
It’s still early, but it appears a similar dynamic may have been at work on the cruise ship. Genetic sequencing found that the viral genomes from different passengers were extremely similar to one another. This suggests that one passenger may first have gotten sick from rodent exposure, then transmitted the virus to other passengers.
Fortunately, the Andes virus doesn’t jump efficiently from human to human. It requires close contact with an infected, symptomatic person.
The 2018 outbreak was contained through isolation and quarantine. And more than 80 healthcare workers who had unprotected contact with patients weren’t infected, which shows how inefficiently the virus moves between people.
This bodes well for the cruise ship outbreak, where symptomatic passengers are being isolated and all others will continue to be monitored. This, along with the virus’ relative inability to hop from one person to another, should limit the outbreak.
And if you’re slated to take a cruise or have other travel plans this summer, I wouldn’t worry about hantavirus. Your risk of acquiring something else – think flu, Covid or norovirus – is much, much higher.
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Dr. Hal Scofield is a physician-scientist at the Oklahoma Medical Research Foundation, and he also serves as Associate Chief of Staff for Research at the Oklahoma City VA Medical Center. Adam Cohen is OMRF’s senior vice president and general counsel. Send your health questions to contact@omrf.org.
