Adam’s Journal
In honor of the NBA playoffs, here’s a question from an Oklahoma Medical Research Foundation co-worker:
I read that Indiana Pacers’ star — and 2025 Thunder championship nemesis — Tyrese Haliburton has been struggling for several months with a case of the shingles on his face. He’s only 26.
I thought shingles was more of a concern for older people, especially because vaccination recommendations start at age 50. Can and should you be vaccinated for shingles if you are younger than 50?
Jenny Lee
Dr. Scofield Prescribes
This weakening of immune control typically begins to happen as people age, which is why standard recommendations for Shingrix, the shingles vaccine, begin at 50. However, younger adults can get shingles, and in recent years we’ve seen an uptick in cases in people in their 20s, 30s and 40s.
Although we’re not sure why, the rise of shingles in younger populations is probably due to a number of factors, with stress and sleep deprivation suspected as contributors. The chicken pox vaccine may also impact shingles trends, although that effect is complicated.
By reducing childhood chickenpox, the vaccine has cut adults’ periodic exposures to the virus. Some experts believe those periodic exposures help boost immunity against shingles.
Meanwhile, those vaccinated people are less likely to carry the strain of the virus that most often reactivates as shingles. As a result, studies indicate their future shingles risk is lower than those who were infected naturally.
Unless a person is immunocompromised — such as individuals with HIV, those undergoing chemotherapy, or those receiving treatment for autoimmune disease — vaccination for those under 50 isn’t routinely recommended.
That’s because the absolute risk for disease remains low. Plus, immunity from the previous shingles vaccine (Zostavax) waned over time, and this may happen with Shingrix, too. So, vaccinating too early might leave less protection later in life, which is when risk is highest.
Still, physicians can legally give the vaccine “off label” to younger adults in certain circumstances. Some doctors might consider vaccination for younger patients who have experienced recurrent shingles or an unusually severe case of the virus, especially if it involved the face or eye.
In such cases, insurance likely would not cover the shots.
So, can you be vaccinated under 50? Yes. But should you consider it? Generally, no, unless you’re immunocompromised or have had a significant prior case of shingles.
–
Dr. Hal Scofield is a physician-scientist at the Oklahoma Medical Research Foundation, and he also serves as Associate Chief of Staff for Research at the Oklahoma City VA Medical Center. Adam Cohen is OMRF’s senior vice president and general counsel. Send your health questions to contact@omrf.org.
