Interleukin-6 deficiency corrects nephritis, lymphocyte abnormalities, and secondary Sjögren’s syndrome features in lupus-prone Sle1.Yaa mice.
Anti-peptidoglycan antibodies and Fcγ receptors are the key mediators of inflammation in Gram-positive sepsis.
Cutting edge: primary innate immune cells respond efficiently to polymeric peptidoglycan, but not to peptidoglycan monomers.
E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin alphaLbeta2-mediated slow leukocyte rolling.