OMRF 2015 Publications

Walsh ME, Bhattacharya A, Sataranatarajan K, Qaisar R, Sloane L, Rahman MM, Kinter M, Van Remmen H. The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging. Aging Cell 14:957-70, 2015 December, PMID: 26290460, PMCID: PMC4693467

Feng J, Huang C, Wren JD, Wang DW, Yan J, Zhang J, Sun Y, Han X, Zhang XA. Tetraspanin CD82: a suppressor of solid tumors and a modulator of membrane heterogeneity. Cancer Metastasis Rev 34:619-33, 2015 December, PMID: 26335499

Bockus LB, Humphries KM. cAMP-dependent Protein Kinase (PKA) Signaling Is Impaired in the Diabetic Heart. J Biol Chem 290:29250-8, 2015 December, PMID: 26468277, PMCID: PMC4705931

Siefert JC, Clowdus EA, Sansam CL. Cell cycle control in the early embryonic development of aquatic animal species. Comp Biochem Physiol C Toxicol Pharmacol 178:8-15, 2015 December, PMID: 26475527, PMCID: PMC4755307

Sankaranarayanan K, Ozga AT, Warinner C, Tito RY, Obregon-Tito AJ, Xu J, Gaffney PM, Jervis LL, Cox D, Stephens L, Foster M, Tallbull G, Spicer P, Lewis CM. Gut Microbiome Diversity among Cheyenne and Arapaho Individuals from Western Oklahoma. Curr Biol 25:3161-9, 2015 December, PMID: 26671671, PMCID: PMC4703035

Zhao J, Wu H, Langefeld CD, Kaufman KM, Kelly JA, Bae SC, Marta E. Alarcón-Riquelme for the BIOLUPUS and GENLES networks., Alarcón GS, Anaya JM, Criswell LA, Freedman BI, Kamen DL, Gilkeson GS, Jacob CO, James JA, Merrill JT, Gaffney PM, Sivils KM, Niewold TB, Petri MA, Song ST, Jeong HJ, Ramsey-Goldman R, Reveille JD, Scofield RH, Stevens AM, Boackle SA, Vilá LM, Chang DM, Song YW, Vyse TJ, Harley JB, Brown EE, Edberg JC, Kimberly RP, Hahn BH, Grossman JM, Tsao BP, La Cava A. Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus. Clin Immunol 161:157-62, 2015 December, PMID: 26385092, PMCID: PMC4658308

Ward JM, James JA, Zhao YD, Webb CF. Antibody Reactivity of B Cells in Lupus Patients with Increased Disease Activity and ARID3a Expression. Antibodies (Basel) 4:354-368, 2015 December, PMID: 28580178, PMCID: PMC5451160

Tafur AJ, Dale G, Cherry M, Wren JD, Mansfield AS, Comp P, Rathbun S, Stoner JA. Prospective evaluation of protein C and factor VIII in prediction of cancer-associated thrombosis. Thromb Res 136:1120-5, 2015 December, PMID: 26475410, PMCID: PMC4679511

Radfar L, Ahmadabadi RE, Masood F, Scofield RH. Biological therapy and dentistry: a review paper. Oral Surg Oral Med Oral Pathol Oral Radiol 120:594-601, 2015 November, PMID: 26372436, PMCID: PMC5206793

Wang H, Kim JJ, Denou E, Gallagher A, Thornton DJ, Shajib MS, Xia L, Schertzer JD, Grencis RK, Philpott DJ, Khan WI. New Role of Nod Proteins in Regulation of Intestinal Goblet Cell Response in the Context of Innate Host Defense in an Enteric Parasite Infection. Infect Immun 84:275-85, 2015 November, PMID: 26527214, PMCID: PMC4694016

Zhou XJ, Mu R, Li C, Nath SK, Zhang YM, Qi YY, Li ZG, Zhao MH, Zhang H. Association of variants in CCR6 with susceptibility to lupus nephritis in Chinese. Arthritis Rheumatol 67:3091-3, 2015 November, PMID: 26138531, PMCID: PMC5385840

Larabee CM, Georgescu C, Wren JD, Plafker SM. Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons. BMC Neurosci 16:76, 2015 November, PMID: 26566974, PMCID: PMC4644300

Coit P, Ognenovski M, Gensterblum E, Maksimowicz-McKinnon K, Wren JD, Sawalha AH. Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity. Epigenetics Chromatin 8:49, 2015 November, PMID: 26609326, PMCID: PMC4659164

Silasi-Mansat R, Zhu H, Georgescu C, Popescu N, Keshari RS, Peer G, Lupu C, Taylor FB, Pereira HA, Kinasewitz G, Lambris JD, Lupu F. Complement inhibition decreases early fibrogenic events in the lung of septic baboons. J Cell Mol Med 19:2549-63, 2015 November, PMID: 26337158, PMCID: PMC4627561

Walsh ME, Bhattacharya A, Liu Y, Van Remmen H. Butyrate prevents muscle atrophy after sciatic nerve crush. Muscle Nerve 52:859-68, 2015 November, PMID: 25727783

Walsh ME, Sloane LB, Fischer KE, Austad SN, Richardson A, Van Remmen H. Use of Nerve Conduction Velocity to Assess Peripheral Nerve Health in Aging Mice. J Gerontol A Biol Sci Med Sci 70:1312-9, 2015 November, PMID: 25477428, PMCID: PMC4612382

Bello GA, Adrianto I, Dumancas GG, Levin AM, Iannuzzi MC, Rybicki BA, Montgomery C. Role of NOD2 Pathway Genes in Sarcoidosis Cases with Clinical Characteristics of Blau Syndrome. Am J Respir Crit Care Med 192:1133-5, 2015 November, PMID: 26517420, PMCID: PMC5447311

Fjeldstad C, Suárez G, Klingler M, Henney HR 3rd, Rabinowicz AL, Pardo G. Dalfampridine Effects Beyond Walking Speed in Multiple Sclerosis. Int J MS Care 17:275-83, 2015 November, PMID: 26664333, PMCID: PMC4673920

Kim K, Bang SY, Lee S, Lee HS, Shim SC, Kang YM, Suh CH, Sun C, Nath SK, Bae SC, Kim TH. An HLA-C amino-acid variant in addition to HLA-B*27 confers risk for ankylosing spondylitis in the Korean population. Arthritis Res Ther 17:342, 2015 November, PMID: 26613595, PMCID: PMC4662802

Dozmorov MG, Dominguez N, Bean K, Macwana SR, Roberts V, Glass E, James JA, Guthridge JM. B-Cell and Monocyte Contribution to Systemic Lupus Erythematosus Identified by Cell-Type-Specific Differential Expression Analysis in RNA-Seq Data. Bioinform Biol Insights 9:11-9, 2015 October, PMID: 26512198, PMCID: PMC4599594

Lareau CA, White BC, Montgomery CG, McKinney BA. dcVar: a method for identifying common variants that modulate differential correlation structures in gene expression data. Front Genet 6:312, 2015 October, PMID: 26539209, PMCID: PMC4609883

Lareau CA, Adrianto I, Levin AM, Iannuzzi MC, Rybicki BA, Montgomery CG. Fine mapping of chromosome 15q25 implicates ZNF592 in neurosarcoidosis patients. Ann Clin Transl Neurol 2:972-7, 2015 October, PMID: 26478897, PMCID: PMC4603380

Devera TS, Lang GA, Lanis JM, Rampuria P, Gilmore CL, James JA, Ballard JD, Lang ML. Memory B Cells Encode Neutralizing Antibody Specific for Toxin B from the Clostridium difficile Strains VPI 10463 and NAP1/BI/027 but with Superior Neutralization of VPI 10463 Toxin B. Infect Immun 84:194-204, 2015 October, PMID: 26502913, PMCID: PMC4693989

Yago T, Tsukamoto H, Liu Z, Wang Y, Thompson LF, McEver RP. Multi-Inhibitory Effects of A2A Adenosine Receptor Signaling on Neutrophil Adhesion Under Flow. J Immunol 195:3880-9, 2015 October, PMID: 26355151, PMCID: PMC4592819

Coutinho de Souza P, Smith N, Atolagbe O, Ziegler J, Njoku C, Lerner M, Ehrenshaft M, Mason RP, Meek B, Plafker SM, Saunders D, Mamedova N, Towner RA. OKN-007 decreases free radical levels in a preclinical F98 rat glioma model. Free Radic Biol Med 87:157-68, 2015 October, PMID: 26119786, PMCID: PMC6208328

Fjeldstad C, Fjeldstad AS, Pardo G. Use of Accelerometers to Measure Real-Life Physical Activity in Ambulatory Individuals with Multiple Sclerosis: A Pilot Study. Int J MS Care 17:215-20, 2015 September, PMID: 26472942, PMCID: PMC4599358

Bourn R, James JA. Preclinical lupus. Curr Opin Rheumatol 27:433-9, 2015 September, PMID: 26125103, PMCID: PMC4651850

Kurien BT, Harris VM, Quadri SM, Coutinho-de Souza P, Cavett J, Moyer A, Ittiq B, Metcalf A, Ramji HF, Truong D, Kumar R, Koelsch KA, Centola M, Payne A, Danda D, Scofield RH. Significantly reduced lymphadenopathy, salivary gland infiltrates and proteinuria in MRL-lpr/lpr mice treated with ultrasoluble curcumin/turmeric: increased survival with curcumin treatment. Lupus Sci Med 2:e000114, 2015 September, PMID: 26380101, PMCID: PMC4567741

Meyer RE, Chuong HH, Hild M, Hansen CL, Kinter M, Dawson DS. Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae. Mol Biol Cell 26:2986-3000, 2015 September, PMID: 26157162, PMCID: PMC4551314

Munroe ME, James JA. Genetics of Lupus Nephritis: Clinical Implications. Semin Nephrol 35:396-409, 2015 September, PMID: 26573543, PMCID: PMC4653095

G'Sell RT, Gaffney PM, Powell DW. A20-Binding Inhibitor of NF-κB Activation 1 is a Physiologic Inhibitor of NF-κB: A Molecular Switch for Inflammation and Autoimmunity. Arthritis Rheumatol 67:2292-302, 2015 September, PMID: 26097105, PMCID: PMC4551579

Renauer P, Coit P, Jeffries MA, Merrill JT, McCune WJ, Maksimowicz-McKinnon K, Sawalha AH. DNA methylation patterns in naïve CD4+ T cells identify epigenetic susceptibility loci for malar rash and discoid rash in systemic lupus erythematosus. Lupus Sci Med 2:e000101, 2015 September, PMID: 26405558, PMCID: PMC4577980

Fisch AS, Yerges-Armstrong LM, Backman JD, Wang H, Donnelly P, Ryan KA, Parihar A, Pavlovich MA, Mitchell BD, O'Connell JR, Herzog W, Harman CR, Wren JD, Lewis JP. Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction. PLoS One 10:e0138795, 2015 September, PMID: 26406321, PMCID: PMC4583223

Fischer A, Ellinghaus D, Nutsua M, Hofmann S, Montgomery CG, Iannuzzi MC, Rybicki BA, Petrek M, Mrazek F, Pabst S, Grohé C, Grunewald J, Ronninger M, Eklund A, Padyukov L, Mihailovic-Vucinic V, Jovanovic D, Sterclova M, Homolka J, Nöthen MM, Herms S, Gieger C, Strauch K, Winkelmann J, Boehm BO, Brand S, Büning C, Schürmann M, Ellinghaus E, Baurecht H, Lieb W, Nebel A, Müller-Quernheim J, Franke A, Schreiber S, GenPhenReSa Consortium.. Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk. Am J Respir Crit Care Med 192:727-36, 2015 September, PMID: 26051272, PMCID: PMC4595678

Bruce IN, O'Keeffe AG, Farewell V, Hanly JG, Manzi S, Su L, Gladman DD, Bae SC, Sanchez-Guerrero J, Romero-Diaz J, Gordon C, Wallace DJ, Clarke AE, Bernatsky S, Ginzler EM, Isenberg DA, Rahman A, Merrill JT, Alarcón GS, Fessler BJ, Fortin PR, Petri M, Steinsson K, Dooley MA, Khamashta MA, Ramsey-Goldman R, Zoma AA, Sturfelt GK, Nived O, Aranow C, Mackay M, Ramos-Casals M, van Vollenhoven RF, Kalunian KC, Ruiz-Irastorza G, Lim S, Kamen DL, Peschken CA, Inanc M, Urowitz MB. Factors associated with damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort. Ann Rheum Dis 74:1706-13, 2015 September, PMID: 24834926, PMCID: PMC4552899

Song K, Herzog BH, Fu J, Sheng M, Bergstrom K, McDaniel JM, Kondo Y, McGee S, Cai X, Li P, Chen H, Xia L. Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice. J Biol Chem 290:20159-66, 2015 August, PMID: 26124270, PMCID: PMC4536426

Levin AM, Adrianto I, Datta I, Iannuzzi MC, Trudeau S, Li J, Drake WP, Montgomery CG, Rybicki BA. Association of HLA-DRB1 with Sarcoidosis Susceptibility and Progression in African Americans. Am J Respir Cell Mol Biol 53:206-16, 2015 August, PMID: 25506722, PMCID: PMC4566045

Roskin KM, Simchoni N, Liu Y, Lee JY, Seo K, Hoh RA, Pham T, Park JH, Furman D, Dekker CL, Davis MM, James JA, Nadeau KC, Cunningham-Rundles C, Boyd SD. IgH sequences in common variable immune deficiency reveal altered B cell development and selection. Sci Transl Med 7:302ra135, 2015 August, PMID: 26311730, PMCID: PMC4584259

Stohl W, Merrill JT, Looney RJ, Buyon J, Wallace DJ, Weisman MH, Ginzler EM, Cooke B, Holloway D, Kaliyaperumal A, Kuchimanchi KR, Cheah TC, Rasmussen E, Ferbas J, Belouski SS, Tsuji W, Zack DJ. Treatment of systemic lupus erythematosus patients with the BAFF antagonist "peptibody" blisibimod (AMG 623/A-623): results from randomized, double-blind phase 1a and phase 1b trials. Arthritis Res Ther 17:215, 2015 August, PMID: 26290435, PMCID: PMC4545922

Parker B, Urowitz MB, Gladman DD, Lunt M, Donn R, Bae SC, Sanchez-Guerrero J, Romero-Diaz J, Gordon C, Wallace DJ, Clarke AE, Bernatsky S, Ginzler EM, Isenberg DA, Rahman A, Merrill JT, Alarcón GS, Fessler BJ, Fortin PR, Hanly JG, Petri M, Steinsson K, Dooley MA, Manzi S, Khamashta MA, Ramsey-Goldman R, Zoma AA, Sturfelt GK, Nived O, Aranow C, Mackay M, Ramos-Casals M, van Vollenhoven RF, Kalunian KC, Ruiz-Irastorza G, Lim SS, Kamen DL, Peschken CA, Inanc M, Bruce IN. Impact of early disease factors on metabolic syndrome in systemic lupus erythematosus: data from an international inception cohort. Ann Rheum Dis 74:1530-6, 2015 August, PMID: 24692585, PMCID: PMC4515988

Sataranatarajan K, Qaisar R, Davis C, Sakellariou GK, Vasilaki A, Zhang Y, Liu Y, Bhaskaran S, McArdle A, Jackson M, Brooks SV, Richardson A, Van Remmen H. Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype. Redox Biol 5:140-148, 2015 August, PMID: 25917273, PMCID: PMC5022075

Griffith AV, Venables T, Shi J, Farr A, van Remmen H, Szweda L, Fallahi M, Rabinovitch P, Petrie HT. Metabolic Damage and Premature Thymus Aging Caused by Stromal Catalase Deficiency. Cell Rep 12:1071-9, 2015 August, PMID: 26257169, PMCID: PMC4797338

Zhu Y, Tchkonia T, Pirtskhalava T, Gower AC, Ding H, Giorgadze N, Palmer AK, Ikeno Y, Hubbard GB, Lenburg M, O'Hara SP, LaRusso NF, Miller JD, Roos CM, Verzosa GC, LeBrasseur NK, Wren JD, Farr JN, Khosla S, Stout MB, McGowan SJ, Fuhrmann-Stroissnigg H, Gurkar AU, Zhao J, Colangelo D, Dorronsoro A, Ling YY, Barghouthy AS, Navarro DC, Sano T, Robbins PD, Niedernhofer LJ, Kirkland JL. The Achilles' heel of senescent cells: from transcriptome to senolytic drugs. Aging Cell 14:644-58, 2015 August, PMID: 25754370, PMCID: PMC4531078

McEver RP. Selectins: initiators of leucocyte adhesion and signalling at the vascular wall. Cardiovasc Res 107:331-9, 2015 August, PMID: 25994174, PMCID: PMC4592324

Sansam CL, Pezza RJ. Connecting by breaking and repairing: mechanisms of DNA strand exchange in meiotic recombination. FEBS J 282:2444-57, 2015 July, PMID: 25953379, PMCID: PMC4573575

Rankin S. Complex elaboration: making sense of meiotic cohesin dynamics. FEBS J 282:2426-43, 2015 July, PMID: 25895170, PMCID: PMC4490075

Coit P, Renauer P, Jeffries MA, Merrill JT, McCune WJ, Maksimowicz-McKinnon K, Sawalha AH. Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells. J Autoimmun 61:29-35, 2015 July, PMID: 26005050, PMCID: PMC4497927

Kurien BT, Danda D, Scofield RH. Therapeutic potential of curcumin and curcumin analogues in rheumatology. Int J Rheum Dis 18:591-3, 2015 July, PMID: 26301972

Hanly JG, Su L, Urowitz MB, Romero-Diaz J, Gordon C, Bae SC, Bernatsky S, Clarke AE, Wallace DJ, Merrill JT, Isenberg DA, Rahman A, Ginzler EM, Petri M, Bruce IN, Dooley MA, Fortin P, Gladman DD, Sanchez-Guerrero J, Steinsson K, Ramsey-Goldman R, Khamashta MA, Aranow C, Alarcón GS, Fessler BJ, Manzi S, Nived O, Sturfelt GK, Zoma AA, van Vollenhoven RF, Ramos-Casals M, Ruiz-Irastorza G, Lim SS, Kalunian KC, Inanc M, Kamen DL, Peschken CA, Jacobsen S, Askanase A, Theriault C, Thompson K, Farewell V. Mood Disorders in Systemic Lupus Erythematosus: Results From an International Inception Cohort Study. Arthritis Rheumatol 67:1837-47, 2015 July, PMID: 25778456, PMCID: PMC4485527

Merrill JT. Connective tissue diseases: Is SLE many single-organ diseases or an overlapping spectrum? Nat Rev Rheumatol 11:385-6, 2015 July, PMID: 25939416

Yago T, Petrich BG, Zhang N, Liu Z, Shao B, Ginsberg MH, McEver RP. Blocking neutrophil integrin activation prevents ischemia-reperfusion injury. J Exp Med 212:1267-81, 2015 July, PMID: 26169939, PMCID: PMC4516797

Pezza RJ. Mechanisms of chromosome segregation in meiosis--new views on the old problem of aneuploidy. FEBS J 282:2424-5, 2015 July, PMID: 25959513, PMCID: PMC4574507

Shao B, Yago T, Setiadi H, Wang Y, Mehta-D'souza P, Fu J, Crocker PR, Rodgers W, Xia L, McEver RP. O-glycans direct selectin ligands to lipid rafts on leukocytes. Proc Natl Acad Sci U S A 112:8661-6, 2015 July, PMID: 26124096, PMCID: PMC4507194

Kurdzo EL, Dawson DS. Centromere pairing--tethering partner chromosomes in meiosis I. FEBS J 282:2458-70, 2015 July, PMID: 25817724, PMCID: PMC4490064

Gorbsky GJ. The spindle checkpoint and chromosome segregation in meiosis. FEBS J 282:2471-87, 2015 July, PMID: 25470754, PMCID: PMC4454629

Evans TM, Jaramillo CA, Sataranatarajan K, Watts L, Sabia M, Qi W, Van Remmen H. The effect of mild traumatic brain injury on peripheral nervous system pathology in wild-type mice and the G93A mutant mouse model of motor neuron disease. Neuroscience 298:410-23, 2015 July, PMID: 25921732, PMCID: PMC4470701

He C, Medley SC, Hu T, Hinsdale ME, Lupu F, Virmani R, Olson LE. PDGFRβ signalling regulates local inflammation and synergizes with hypercholesterolaemia to promote atherosclerosis. Nat Commun 6:7770, 2015 July, PMID: 26183159, PMCID: PMC4507293

Ivannikov MV, Van Remmen H. Sod1 gene ablation in adult mice leads to physiological changes at the neuromuscular junction similar to changes that occur in old wild-type mice. Free Radic Biol Med 84:254-262, 2015 July, PMID: 25841780, PMCID: PMC4762177

James JA, Thompson LF, Budd RC. J. Donald Capra, M.D. (1937-2015). J Immunol 194:5575-6, 2015 June, PMID: 26048964

Sandhya P, Jeyaseelan L, Scofield RH, Danda D. Clinical Characteristics and Outcome of Primary Sjogren's Syndrome: A Large Asian Indian Cohort. Open Rheumatol J 9:36-45, 2015 June, PMID: 26161156, PMCID: PMC4493630

Fernandes J, Weddle A, Kinter CS, Humphries KM, Mather T, Szweda LI, Kinter M. Lysine Acetylation Activates Mitochondrial Aconitase in the Heart. Biochemistry 54:4008-18, 2015 June, PMID: 26061789, PMCID: PMC4513942

Iwayama T, Steele C, Yao L, Dozmorov MG, Karamichos D, Wren JD, Olson LE. PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity. Genes Dev 29:1106-19, 2015 June, PMID: 26019175, PMCID: PMC4470280

de Souza PC, Smith N, Pody R, He T, Njoku C, Silasi-Mansat R, Lupu F, Meek B, Chen H, Dong Y, Saunders D, Orock A, Hodges E, Colijn S, Mamedova N, Towner RA. OKN-007 decreases VEGFR-2 levels in a preclinical GL261 mouse glioma model. Am J Nucl Med Mol Imaging 5:363-78, 2015 June, PMID: 26269774, PMCID: PMC4529590

Buyon JP, Cohen P, Merrill JT, Gilkeson G, Kaplan M, James J, McCune WJ, Bernatsky S, Elkon K. A highlight from the LUPUS 2014 meeting: eight great ideas. Lupus Sci Med 2:e000087, 2015 June, PMID: 26167290, PMCID: PMC4493165

Wu YY, Georg I, Díaz-Barreiro A, Varela N, Lauwerys B, Kumar R, Bagavant H, Castillo-Martín M, El Salem F, Marañón C, Alarcón-Riquelme ME. Concordance of increased B1 cell subset and lupus phenotypes in mice and humans is dependent on BLK expression levels. J Immunol 194:5692-702, 2015 June, PMID: 25972485, PMCID: PMC4458437

Kaur K, Zheng NY, Smith K, Huang M, Li L, Pauli NT, Henry Dunand CJ, Lee JH, Morrissey M, Wu Y, Joachims ML, Munroe ME, Lau D, Qu X, Krammer F, Wrammert J, Palese P, Ahmed R, James JA, Wilson PC. High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination. PLoS One 10:e0125618, 2015 May, PMID: 25951191, PMCID: PMC4423960

Lu X, Zoller EE, Weirauch MT, Wu Z, Namjou B, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Reveille JD, Anaya JM, James JA, Sivils KL, Criswell LA, Vilá LM, Alarcón-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Joo YB, Choi J, Bae SC, Boackle SA, Graham DC, Vyse TJ, Guthridge JM, Gaffney PM, Langefeld CD, Kelly JA, Greis KD, Kaufman KM, Harley JB, Kottyan LC. Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. Am J Hum Genet 96:731-9, 2015 May, PMID: 25865496, PMCID: PMC4570281

Kwak HB, Lee Y, Kim JH, Van Remmen H, Richardson AG, Lawler JM. MnSOD overexpression reduces fibrosis and pro-apoptotic signaling in the aging mouse heart. J Gerontol A Biol Sci Med Sci 70:533-44, 2015 May, PMID: 25016531, PMCID: PMC4462657

Yapundich R, Applebee A, Bethoux F, Goldman MD, Hutton GJ, Mass M, Pardo G, Klingler M, Henney HR 3rd, Blight AR, Carrazana EJ. Evaluation of Dalfampridine Extended Release 5 and 10 mg in Multiple Sclerosis: A Randomized Controlled Trial. Int J MS Care 17:138-45, 2015 May, PMID: 26052259, PMCID: PMC4455866

Pruenster M, Kurz AR, Chung KJ, Cao-Ehlker X, Bieber S, Nussbaum CF, Bierschenk S, Eggersmann TK, Rohwedder I, Heinig K, Immler R, Moser M, Koedel U, Gran S, McEver RP, Vestweber D, Verschoor A, Leanderson T, Chavakis T, Roth J, Vogl T, Sperandio M. Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion. Nat Commun 6:6915, 2015 April, PMID: 25892652, PMCID: PMC4411303

Kovats S. Estrogen receptors regulate innate immune cells and signaling pathways. Cell Immunol 294:63-9, 2015 April, PMID: 25682174, PMCID: PMC4380804

Lee CY, Horn HF, Stewart CL, Burke B, Bolcun-Filas E, Schimenti JC, Dresser ME, Pezza RJ. Mechanism and regulation of rapid telomere prophase movements in mouse meiotic chromosomes. Cell Rep 11:551-63, 2015 April, PMID: 25892231, PMCID: PMC4417006

Chaaban H, Keshari RS, Silasi-Mansat R, Popescu NI, Mehta-D'Souza P, Lim YP, Lupu F. Inter-α inhibitor protein and its associated glycosaminoglycans protect against histone-induced injury. Blood 125:2286-96, 2015 April, PMID: 25631771, PMCID: PMC4383802

Coit P, Yalavarthi S, Ognenovski M, Zhao W, Hasni S, Wren JD, Kaplan MJ, Sawalha AH. Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils. J Autoimmun 58:59-66, 2015 April, PMID: 25638528, PMCID: PMC4363276

Wiley MM, Muthukumar V, Griffin TM, Griffin CT. SWI/SNF chromatin-remodeling enzymes Brahma-related gene 1 (BRG1) and Brahma (BRM) are dispensable in multiple models of postnatal angiogenesis but are required for vascular integrity in infant mice. J Am Heart Assoc 4, 2015 April, PMID: 25904594, PMCID: PMC4579958

Clark EG, Knoll G, Bugeja A, Burns KD, Scofield RH. Lupus after kidney donation to an affected male relative. Transplantation 99:e27-8, 2015 April, PMID: 25827324, PMCID: PMC5664938

Gandhapudi SK, Tan C, Marino JH, Taylor AA, Pack CC, Gaikwad J, Van De Wiele CJ, Wren JD, Teague TK. IL-18 acts in synergy with IL-7 to promote ex vivo expansion of T lymphoid progenitor cells. J Immunol 194:3820-8, 2015 April, PMID: 25780034, PMCID: PMC4536257

Maier-Moore JS, Kurien BT, D'Souza A, Bockus L, Asfa S, Dorri Y, Hubbell S, Yeliosof O, Obeso D, Schoeb TR, Jonsson R, Scofield RH. Passive transfer of antibodies to the linear epitope 60 kD Ro 273-289 induces features of Sjögren's syndrome in naive mice. Clin Exp Immunol 180:19-27, 2015 April, PMID: 25370295, PMCID: PMC4367090

Askanase A, Li X, Pong A, Shum K, Kamp S, Carthen F, Aberle T, Hanrahan L, Daly P, Giles J, Merrill JT. Preliminary test of the LFA rapid evaluation of activity in lupus (LFA-REAL): an efficient outcome measure correlates with validated instruments. Lupus Sci Med 2:e000075, 2015 March, PMID: 25861457, PMCID: PMC4378376

Chang B, Tessneer KL, McManus J, Liu X, Hahn S, Pasula S, Wu H, Song H, Chen Y, Cai X, Dong Y, Brophy ML, Rahman R, Ma JX, Xia L, Chen H. Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development. Nat Commun 6:6380, 2015 March, PMID: 25871009, PMCID: PMC4397653

Tulunay A, Dozmorov MG, Ture-Ozdemir F, Yilmaz V, Eksioglu-Demiralp E, Alibaz-Oner F, Ozen G, Wren JD, Saruhan-Direskeneli G, Sawalha AH, Direskeneli H. Activation of the JAK/STAT pathway in Behcet's disease. Genes Immun 16:176, 2015 March, PMID: 25739881

Kim K, Bang SY, Lee HS, Cho SK, Choi CB, Sung YK, Kim TH, Jun JB, Yoo DH, Kang YM, Kim SK, Suh CH, Shim SC, Lee SS, Lee J, Chung WT, Choe JY, Shin HD, Lee JY, Han BG, Nath SK, Eyre S, Bowes J, Pappas DA, Kremer JM, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Ärlestig L, Okada Y, Diogo D, Liao KP, Karlson EW, Raychaudhuri S, Rantapää-Dahlqvist S, Martin J, Klareskog L, Padyukov L, Gregersen PK, Worthington J, Greenberg JD, Plenge RM, Bae SC. High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. Ann Rheum Dis 74:e13, 2015 March, PMID: 24532676, PMCID: PMC4467986

Obregon-Tito AJ, Tito RY, Metcalf J, Sankaranarayanan K, Clemente JC, Ursell LK, Zech Xu Z, Van Treuren W, Knight R, Gaffney PM, Spicer P, Lawson P, Marin-Reyes L, Trujillo-Villarroel O, Foster M, Guija-Poma E, Troncoso-Corzo L, Warinner C, Ozga AT, Lewis CM. Subsistence strategies in traditional societies distinguish gut microbiomes. Nat Commun 6:6505, 2015 March, PMID: 25807110, PMCID: PMC4386023

Martins M, Williams AH, Comeau M, Marion M, Ziegler JT, Freedman BI, Merrill JT, Glenn SB, Kelly JA, Sivils KM, James JA, Guthridge JM, Alarcón-Riquelme ME, Bae SC, Kim JH, Kim D, Anaya JM, Boackle SA, Criswell LA, Kimberly RP, Alarcón GS, Brown EE, Vilá LM, Petri MA, Ramsey-Goldman R, Niewold TB, Tsao BP, Gilkeson GS, Kamen DL, Jacob CO, Stevens AM, Gaffney PM, Harley JB, Langefeld CD, Fesel C. Genetic association of CD247 (CD3ζ) with SLE in a large-scale multiethnic study. Genes Immun 16:142-50, 2015 March, PMID: 25569266, PMCID: PMC4371129

Fayyaz A, Igoe A, Kurien BT, Danda D, James JA, Stafford HA, Scofield RH. Haematological manifestations of lupus. Lupus Sci Med 2:e000078, 2015 March, PMID: 25861458, PMCID: PMC4378375

Matsuzaki S, Humphries KM. Selective inhibition of deactivated mitochondrial complex I by biguanides. Biochemistry 54:2011-21, 2015 March, PMID: 25719498, PMCID: PMC4440585

Lane RS, Fu Y, Matsuzaki S, Kinter M, Humphries KM, Griffin TM. Mitochondrial respiration and redox coupling in articular chondrocytes. Arthritis Res Ther 17:54, 2015 March, PMID: 25889867, PMCID: PMC4384316

Sansam CG, Goins D, Siefert JC, Clowdus EA, Sansam CL. Cyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation. Genes Dev 29:555-66, 2015 March, PMID: 25737283, PMCID: PMC4358407

Schubert RD, Hu Y, Kumar G, Szeto S, Abraham P, Winderl J, Guthridge JM, Pardo G, Dunn J, Steinman L, Axtell RC. IFN-β treatment requires B cells for efficacy in neuroautoimmunity. J Immunol 194:2110-6, 2015 March, PMID: 25646307, PMCID: PMC4340715

Slight-Webb SR, Bagavant H, Crowe SR, James JA. Influenza A (H1N1) virus infection triggers severe pulmonary inflammation in lupus-prone mice following viral clearance. J Autoimmun 57:66-76, 2015 February, PMID: 25563403, PMCID: PMC4324011

Edgar CE, Terrell DR, Vesely SK, Wren JD, Dozmorov IM, Niewold TB, Brown M, Zhou F, Frank MB, Merrill JT, Kremer Hovinga JA, Lämmle B, James JA, George JN, Farris AD. Ribosomal and immune transcripts associate with relapse in acquired ADAMTS13-deficient thrombotic thrombocytopenic purpura. PLoS One 10:e0117614, 2015 February, PMID: 25671313, PMCID: PMC4324966

Ratliff ML, Ward JM, Merrill JT, James JA, Webb CF. Differential expression of the transcription factor ARID3a in lupus patient hematopoietic progenitor cells. J Immunol 194:940-9, 2015 February, PMID: 25535283, PMCID: PMC4297684

Yaciuk JC, Pan Y, Schwarz K, Pan ZJ, Maier-Moore JS, Kosanke SD, Lawrence C, Farris AD. Defective selection of thymic regulatory T cells accompanies autoimmunity and pulmonary infiltrates in Tcra-deficient mice double transgenic for human La/Sjögren's syndrome-B and human La-specific TCR. J Immunol 194:1514-22, 2015 February, PMID: 25582858, PMCID: PMC4323622

Sivakumar S, Gorbsky GJ. Spatiotemporal regulation of the anaphase-promoting complex in mitosis. Nat Rev Mol Cell Biol 16:82-94, 2015 February, PMID: 25604195, PMCID: PMC4386896

Aggarwal R, Anaya JM, Koelsch KA, Kurien BT, Scofield RH. Association between Secondary and Primary Sjögren's Syndrome in a Large Collection of Lupus Families. Autoimmune Dis 2015:298506, 2015 January, PMID: 26246904, PMCID: PMC4515287

Kurien BT, Danda D, Scofield RH. Fingerprint deposition on nitrocellulose and polyvinylidene difluoride membranes using alkaline phosphatase. Methods Mol Biol 1312:481-5, 2015 January, PMID: 26044031

Kurien BT, Scofield RH. Western blotting: an introduction. Methods Mol Biol 1312:17-30, 2015 January, PMID: 26043986

Plafker KS, Plafker SM. The ubiquitin-conjugating enzyme UBE2E3 and its import receptor importin-11 regulate the localization and activity of the antioxidant transcription factor NRF2. Mol Biol Cell 26:327-38, 2015 January, PMID: 25378586, PMCID: PMC4294679

Kurien BT, Danda D, Bachmann MP, Scofield RH. SDS-PAGE to Immunoblot in One Hour. Methods Mol Biol 1312:449-54, 2015 January, PMID: 26044026

Dsouza A, Scofield RH. Protein Stains to Detect Antigen on Membranes. Methods Mol Biol 1314:33-40, 2015 January, PMID: 26139252

Astarita JL, Cremasco V, Fu J, Darnell MC, Peck JR, Nieves-Bonilla JM, Song K, Kondo Y, Woodruff MC, Gogineni A, Onder L, Ludewig B, Weimer RM, Carroll MC, Mooney DJ, Xia L, Turley SJ. The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture. Nat Immunol 16:75-84, 2015 January, PMID: 25347465, PMCID: PMC4270928

Yeliosof O, Scofield RH. Grid-immunoblotting. Methods Mol Biol 1312:375-8, 2015 January, PMID: 26044018

Wanagat J, Ahmadieh N, Bielas JH, Ericson NG, Van Remmen H. Skeletal muscle mitochondrial DNA deletions are not increased in CuZn-superoxide dismutase deficient mice. Exp Gerontol 61:15-9, 2015 January, PMID: 25449857, PMCID: PMC4289650

Jaiswal S, Smith K, Ramirez A, Woda M, Pazoles P, Shultz LD, Greiner DL, Brehm MA, Mathew A. Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice. Exp Biol Med (Maywood) 240:67-78, 2015 January, PMID: 25125497, PMCID: PMC4446989

Jackson KW, Christiansen VJ, Yadav VR, Silasi-Mansat R, Lupu F, Awasthi V, Zhang RR, McKee PA. Suppression of tumor growth in mice by rationally designed pseudopeptide inhibitors of fibroblast activation protein and prolyl oligopeptidase. Neoplasia 17:43-54, 2015 January, PMID: 25622898, PMCID: PMC4309729

Towner RA, Smith N, Saunders D, Carrizales J, Lupu F, Silasi-Mansat R, Ehrenshaft M, Mason RP. In vivo targeted molecular magnetic resonance imaging of free radicals in diabetic cardiomyopathy within mice. Free Radic Res 49:1140-6, 2015 January, PMID: 25968951, PMCID: PMC4867554

Kottyan LC, Zoller EE, Bene J, Lu X, Kelly JA, Rupert AM, Lessard CJ, Vaughn SE, Marion M, Weirauch MT, Namjou B, Adler A, Rasmussen A, Glenn S, Montgomery CG, Hirschfield GM, Xie G, Coltescu C, Amos C, Li H, Ice JA, Nath SK, Mariette X, Bowman S, UK Primary Sjögren's Syndrome Registry., Rischmueller M, Lester S, Brun JG, Gøransson LG, Harboe E, Omdal R, Cunninghame-Graham DS, Vyse T, Miceli-Richard C, Brennan MT, Lessard JA, Wahren-Herlenius M, Kvarnström M, Illei GG, Witte T, Jonsson R, Eriksson P, Nordmark G, Ng WF, UK Primary Sjögren's Syndrome Registry., Anaya JM, Rhodus NL, Segal BM, Merrill JT, James JA, Guthridge JM, Scofield RH, Alarcon-Riquelme M, Bae SC, Boackle SA, Criswell LA, Gilkeson G, Kamen DL, Jacob CO, Kimberly R, Brown E, Edberg J, Alarcón GS, Reveille JD, Vilá LM, Petri M, Ramsey-Goldman R, Freedman BI, Niewold T, Stevens AM, Tsao BP, Ying J, Mayes MD, Gorlova OY, Wakeland W, Radstake T, Martin E, Martin J, Siminovitch K, Moser Sivils KL, Gaffney PM, Langefeld CD, Harley JB, Kaufman KM. The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share. Hum Mol Genet 24:582-96, 2015 January, PMID: 25205108, PMCID: PMC4275071

Vaughn SE, Foley C, Lu X, Patel ZH, Zoller EE, Magnusen AF, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath S, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Reveille JD, Anaya JM, James JA, Moser KL, Criswell LA, Vilá LM, Alarcón-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Binjoo Y, Choi J, Bae SC, Boackle SA, Vyse TJ, Guthridge JM, Namjou B, Gaffney PM, Langefeld CD, Kaufman KM, Kelly JA, Harley IT, Harley JB, Kottyan LC. Lupus risk variants in the PXK locus alter B-cell receptor internalization. Front Genet 5:450, 2015 January, PMID: 25620976, PMCID: PMC4288052

Kurien BT, Scofield RH. Analysis of antibody clonotype by affinity immunoblotting. Methods Mol Biol 1312:109-17, 2015 January, PMID: 26043996

Bockus LB, Scofield RH. Phosphoprotein Detection on Protein Electroblot Using a Phosphate-Specific Fluorophore. Methods Mol Biol 1314:263-71, 2015 January, PMID: 26139274

LaBryer L, Sawh R, McLaurin C, Scofield RH. Calcitonin-Secreting Neuroendocrine Carcinoma of Larynx with Metastasis to Thyroid. Case Rep Endocrinol 2015:606389, 2015 January, PMID: 26491576, PMCID: PMC4600946

Kurien BT, Scofield RH. Other notable protein blotting methods: a brief review. Methods Mol Biol 1312:487-503, 2015 January, PMID: 26044032

Wang S, Wiley GB, Kelly JA, Gaffney PM. Disease mechanisms in rheumatology--tools and pathways: defining functional genetic variants in autoimmune diseases. Arthritis Rheumatol 67:1-10, 2015 January, PMID: 25132667, PMCID: PMC4298761

Amaya-Amaya J, Rojas-Villarraga A, Molano-Gonzalez N, Montoya-Sánchez L, Nath SK, Anaya JM. GDF15(MIC1) H6D Polymorphism Does Not Influence Cardiovascular Disease in a Latin American Population with Rheumatoid Arthritis. J Immunol Res 2015:270763, 2015 January, PMID: 26090487, PMCID: PMC4451155

Kurien BT, Scofield RH. Western blotting of high and low molecular weight proteins using heat. Methods Mol Biol 1312:247-55, 2015 January, PMID: 26044007

Orbai AM, Truedsson L, Sturfelt G, Nived O, Fang H, Alarcón GS, Gordon C, Merrill J, Fortin PR, Bruce IN, Isenberg DA, Wallace DJ, Ramsey-Goldman R, Bae SC, Hanly JG, Sanchez-Guerrero J, Clarke AE, Aranow CB, Manzi S, Urowitz MB, Gladman DD, Kalunian KC, Costner MI, Werth VP, Zoma A, Bernatsky S, Ruiz-Irastorza G, Khamashta MA, Jacobsen S, Buyon JP, Maddison P, Dooley MA, Van Vollenhoven RF, Ginzler E, Stoll T, Peschken C, Jorizzo JL, Callen JP, Lim SS, Fessler BJ, Inanc M, Kamen DL, Rahman A, Steinsson K, Franks AG Jr, Sigler L, Hameed S, Pham N, Brey R, Weisman MH, McGwin G Jr, Magder LS, Petri M. Anti-C1q antibodies in systemic lupus erythematosus. Lupus 24:42-9, 2015 January, PMID: 25124676, PMCID: PMC4268323

Kurien BT, Scofield RH. Multiple Immunoblots by Passive Diffusion of Proteins from a Single SDS-PAGE Gel. Methods Mol Biol 1312:77-86, 2015 January, PMID: 26043992