2025 Scientific Publications
All Publications
Inamo J, Keegan J, Griffith A, Ghosh T, Horisberger A, Howard K, Pulford JF, Murzin E, Hancock B, Dominguez ST, Gurra MG, Gurajala S, Jonsson AH, Seifert JA, Feser ML, Norris JM, Cao Y, Apruzzese W, Bridges SL, Bykerk VP, Goodman S, Donlin LT, Firestein GS, Bathon JM, Hughes LB, Filer A, Pitzalis C, Anolik JH, Moreland L, Hacohen N, Guthridge JM, James JA, Cuda CM, Perlman H, Brenner MB, Raychaudhuri S, Sparks JA, Accelerating Medicines Partnership RA/SLE Network, Holers VM, Deane KD, Lederer J, Rao DA, Zhang F. Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis. J Clin Invest 135, 2025 March, PMID: 40091833, PMCID: PMC11910230
Murach KA, Englund DA, Chambers TL, Dungan CM, Porter HL, Wren JD, Freeman WM, Dupont-Versteegden EE, Wen Y. A satellite cell-dependent epigenetic fingerprint in skeletal muscle identity genes after lifelong physical activity. FASEB J 39:e70435, 2025 March, PMID: 40047419, PMCID: PMC11884312
Lin SJ, Huang K, Petree C, Qin W, Varshney P, Varshney GK. Optimizing gRNA selection for high-penetrance F0 CRISPR screening for interrogating disease gene function. Nucleic Acids Res 53, 2025 February, PMID: 40103232
Wu C, Chen D, Stout MB, Wu M, Wang S. Hallmarks of ovarian aging. Trends Endocrinol Metab, 2025 February, PMID: 40000274
Zaslavsky ME, Craig E, Michuda JK, Sehgal N, Ram-Mohan N, Lee JY, Nguyen KD, Hoh RA, Pham TD, Röltgen K, Lam B, Parsons ES, Macwana SR, DeJager W, Drapeau EM, Roskin KM, Cunningham-Rundles C, Moody MA, Haynes BF, Goldman JD, Heath JR, Chinthrajah RS, Nadeau KC, Pinsky BA, Blish CA, Hensley SE, Jensen K, Meyer E, Balboni I, Utz PJ, Merrill JT, Guthridge JM, James JA, Yang S, Tibshirani R, Kundaje A, Boyd SD. Disease diagnostics using machine learning of B cell and T cell receptor sequences. Science 387:eadp2407, 2025 February, PMID: 39977494
Gui H, Lessard CJ, Liu J, Li M, Adrianto I. Editorial: Integrative genetics and multi-omics of complex human disorders. Front Genet 16:1574431, 2025 February, PMID: 40061127, PMCID: PMC11885495
Scofield RH, Wren JD, Lewis VM. The toll like receptor 7 pathway and the sex bias of systemic lupus erythematosus. Front Immunol 16:1479814, 2025 February, PMID: 40051623, PMCID: PMC11882868
Anderson M, Scofield RH. The "Fixed Period," the Wildfire News, and an Unpublished Manuscript: Osler's Farewell Speech Revisited in Geographical Breadth and Emotional Depth. Am J Med Sci, 2025 February, PMID: 39947325
Drumond-Bock AL, Beckstead MJ. Ketones on the Brain: Can Diet Help Turn the Tables on Parkinson's?-Commentary on Mahajan et al. (2024). Eur J Neurosci 61:e70025, 2025 February, PMID: 39937087
Yuan X, Qin X, Takemoto K, Zhao J, Sanderson M, Xu X, Zhang Y, Helke KL, Jacobs Wolf B, Guthridge JM, James JA, Zhou X, Assassi S, Feghali-Bostwick C, Wang D, Sun L, Tsao BP. Human hypofunctional NCF1 variants promote pulmonary fibrosis in the bleomycin-induced mouse model and patients with systemic sclerosis via expansion of SPP1( ) monocytes-derived macrophages. Ann Rheum Dis 84:294-306, 2025 February, PMID: 39919902, PMCID: PMC11907366
Sklivas AB, Hettinger ZR, Rose S, Mantuano A, Confides AL, Rigsby S, Peelor FF 3rd, Miller BF, Butterfield TA, Dupont-Versteegden EE. Responses of skeletal muscle to mechanical stimuli in female rats following and during muscle disuse atrophy. J Appl Physiol (1985), 2025 January, PMID: 39884317
Rajala R, Griffin CT. Endothelial protease-activated receptor 4: impotent or important? Front Cardiovasc Med 12:1541879, 2025 January, PMID: 39935714, PMCID: PMC11810968
Merrill JT, Gaudreau MC, D'Silva KM. Reply. Arthritis Rheumatol, 2025 January, PMID: 39953664
Radhakrishna U, Kuracha MR, Hamzavi I, Saiyed N, Prajapati J, Rawal RM, Uppala LV, Damiani G, Ratnamala U, Nath SK. Impaired Molecular Mechanisms Contributing to Chronic Pain in Patients with Hidradenitis Suppurativa: Exploring Potential Biomarkers and Therapeutic Targets. Int J Mol Sci 26, 2025 January, PMID: 39940809, PMCID: PMC11817842
Zahoor I, Nematullah M, Ahmed ME, Fatma M, Sajad M, Ayasolla K, Cerghet M, Palaniyandi S, Ceci V, Carrera G, Buttari F, Centonze D, Mao-Draayer Y, Rattan R, Chiurchiù V, Giri S. Maresin-1 promotes neuroprotection and modulates metabolic and inflammatory responses in disease-associated cell types in preclinical models of Multiple Sclerosis. J Biol Chem:108226, 2025 January, PMID: 39864620, PMCID: PMC11903811
Griffin TM, Komaravolu RK, Lopes EBP, Mehta-D'souza P, Conner T, Kovats T, Kovats S, Allen M, Harris P, Humphrey MB, Welhaven HD, Brahmachary P, June RK. Exercise induces dynamic changes in intra-articular metabolism and inflammation associated with remodeling of the infrapatellar fat pad in mice. Sci Rep 15:2428, 2025 January, PMID: 39827311, PMCID: PMC11743197
Brown JL, Xu H, Duggan E, Rosenfeld CS, Van Remmen H. Pharmacological reduction of lipid hydroperoxides as a potential modulator of sarcopenia. J Physiol, 2025 January, PMID: 39777675
Laumonnerie C, Shamambo M, Stabley DR, Lewis TL Jr, Trivedi N, Howell D, Solecki DJ. Siah2 antagonism of Pard3/JamC modulates Ntn1-Dcc signaling to regulate cerebellar granule neuron germinal zone exit. Nat Commun 16:355, 2025 January, PMID: 39774925, PMCID: PMC11706986
Strucinska K, Kneis P, Pennington T, Cizio K, Szybowska P, Morgan A, Weertman J, Lewis TL Jr. Fis1 is required for the development of the dendritic mitochondrial network in pyramidal cortical neurons. bioRxiv, 2025 January, PMID: 39829888, PMCID: PMC11741399
Gurrea-Rubio M, Lin F, Wicha MS, Mao-Draayer Y, Fox DA. Ligands of CD6: roles in the pathogenesis and treatment of cancer. Front Immunol 15:1528478, 2025 January, PMID: 39840036, PMCID: PMC11747410
Plafker KS, Georgescu C, Pezant N, Pranay A, Plafker SM. Sulforaphane acutely activates multiple starvation response pathways. Front Nutr 11:1485466, 2025 January, PMID: 39867556, PMCID: PMC11758633
Dyson G, Barrett M, Schlupp L, Prinz E, Hannebut N, Szymczak A, Brawner CM, Jeffries MA. Ketogenic Diet-Associated Worsening of Osteoarthritis Histologic Secerity, Increased Pain Sensitivity and Gut Microbiome Dysbiosis in Mice. ACR Open Rheumatol 7:e11794, 2025 January, PMID: 39853943, PMCID: PMC11760994
De Kumar B, Krishnan J. Guidelines to Analyze ChIP-Seq Data: Journey Through QC and Analysis Considerations. Methods Mol Biol 2889:193-206, 2025 January, PMID: 39745614
Rallabandi HR, Singh MK, Looger LL, Nath SK. Defining Mechanistic Links Between the Non-Coding Variant rs17673553 in CLEC16A and Lupus Susceptibility. Int J Mol Sci 26, 2025 January, PMID: 39796169, PMCID: PMC11720054
