2024 Scientific Publications

All Publications

Park J, Kirkland JG. The role of the Polybromo-associated BAF complex in development. Biochem Cell Biol, 2024 November, PMID: 39541575

Blankenship HE, Carter KA, Pham KD, Cassidy NT, Markiewicz AN, Thellmann MI, Sharpe AL, Freeman WM, Beckstead MJ. VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction. Nat Commun 15:9673, 2024 November, PMID: 39516200, PMCID: PMC11549218

Zhang Y, Liu Y, Qin W, Zheng S, Xiao J, Xia X, Yuan X, Zeng J, Shi Y, Zhang Y, Ma H, Varshney GK, Fei JF, Liu Y. Cytosine base editors with increased PAM and deaminase motif flexibility for gene editing in zebrafish. Nat Commun 15:9526, 2024 November, PMID: 39496611, PMCID: PMC11535530

Noaiseh G, Deboo A, King JK, Varadhachary A, Sarka G, Goodman BP, Hammitt KM, Frantsve-Hawley J, Fox R, Baker MC, Danielides S, Mandel S, Pavlakis PP, Scofield RH, Wallace DJ, Carteron N, Carsons S. Recommendations for Aligned Nomenclature of Peripheral Nervous System Disorders Across Rheumatology and Neurology. Arthritis Rheumatol, 2024 November, PMID: 39489692

Langford JB, Ahmed E, Fang M, Cupp-Sutton K, Smith K, Wu S. Strategies for Top-Down Hydrogen Deuterium Exchange-Mass Spectrometry: A Mini Review and Perspective. J Mass Spectrom 59:e5097, 2024 November, PMID: 39402881

Werth VP, Merrill JT, Furie R, Dörner T, van Vollenhoven R, Lipsky P, Weiswasser M, Korish S, Schafer PH, Stern M, Li S, Delev N. Effect of iberdomide on cutaneous manifestations in systemic lupus erythematosus: a randomized phase 2 clinical trial. J Am Acad Dermatol, 2024 October, PMID: 39461504

Barish S, Lin SJ, Maroofian R, Gezdirici A, Alhebby H, Trimouille A, Biderman Waberski M, Mitani T, Huber I, Tveten K, Holla ØL, Busk ØL, Houlden H, Ghayoor Karimiani E, Beiraghi Toosi M, Shervin Badv R, Najarzadeh Torbati P, Eghbal F, Akhondian J, Al Safar A, Alswaid A, Zifarelli G, Bauer P, Marafi D, Fatih JM, Huang K, Petree C, Calame DG, von der Lippe C, Alkuraya FS, Wali S, Lupski JR, Varshney GK, Posey JE, Pehlivan D. Homozygous variants in WDR83OS lead to a neurodevelopmental disorder with hypercholanemia. Am J Hum Genet, 2024 October, PMID: 39471804, PMCID: PMC11568760

Patterson AS, Dugdale J, Koleilat A, Krauss A, Hernandez-Herrera GA, Wallace JG, Petree C, Varshney GK, Schimmenti LA. Vital Dye Uptake of YO-PRO-1 and DASPEI Depends Upon Mechanoelectrical Transduction Function in Zebrafish Hair Cells. J Assoc Res Otolaryngol, 2024 October, PMID: 39433714

Fava A, Wagner CA, James JA. Role of Autoantibodies in Lupus Nephritis: reply. Arthritis Rheumatol, 2024 October, PMID: 39415486

Chu D, Schwartz N, Ampudia J, Guthridge J, James J, Buyon JP, Connelly S, Fung M, Ng CT, Accelerating Medicines Partnership: RA/SLE Network, Fava A, Petri M, Mohan C, Putterman C. Soluble urine activated leukocyte cell adhesion molecule is a strong predictor of lupus nephritis. Rheumatology (Oxford), 2024 October, PMID: 39404817

Nguyen HVM, Ran Q, Salmon AB, Ahn B, Chiao YA, Bhaskaran S, Richardson A. Mouse Models Used to Test the Role of Reactive Oxygen Species in Aging and Age-Related Chronic Diseases. Free Radic Biol Med, 2024 October, PMID: 39419456

Zarzycka W, Kobak KA, King CJ, Peelor FF 3rd, Miller BF, Chiao YA. Hyperactive mTORC1/4EBP1 signaling dysregulates proteostasis and accelerates cardiac aging. Geroscience, 2024 October, PMID: 39379739

Ree R, Lin SJ, Sti Dahl LO, Huang K, Petree C, Varshney GK, Arnesen T. Naa80 is required for actin N-terminal acetylation and normal hearing in zebrafish. Life Sci Alliance 7, 2024 October, PMID: 39384430, PMCID: PMC11465159

Rajala R, Cleuren ACA, Griffin CT. Acetaminophen Overdose Reveals PAR4 as a Low-Expressing but Potent Receptor on the Hepatic Endothelium in Mice. Arterioscler Thromb Vasc Biol, 2024 October, PMID: 39360412

Ramirez-Sagredo A, Sunny AT, Cupp-Sutton KA, Chowdhury T, Zhao Z, Wu S, Chiao YA. Characterizing age-related changes in intact mitochondrial proteoforms in murine hearts using quantitative top-down proteomics. Clin Proteomics 21:57, 2024 September, PMID: 39343872, PMCID: PMC11440756

Laumonnerie C, Shamambo M, Stabley DR, Lewis TL Jr, Trivedi N, Howell D, Solecki DJ. Antagonistic action of Siah2 and Pard3/JamC to promote germinal zone exit of differentiated cerebellar granule neurons by modulating Ntn1 signaling via Dcc. Res Sq, 2024 September, PMID: 39399669, PMCID: PMC11469462

Yuan X, Qin X, Takemoto K, Zhao J, Sanderson M, Xu X, Zhang Y, Helke KL, Jacobs Wolf B, Guthridge JM, James JA, Zhou X, Assassi S, Feghali-Bostwick C, Wang D, Sun L, Tsao BP. Human hypofunctional NCF1 variants promote pulmonary fibrosis in the bleomycin-induced mouse model and patients with systemic sclerosis via expansion of SPP1( ) monocytes-derived macrophages. Ann Rheum Dis, 2024 September, PMID: 39299725

Musci RV, Fuqua JD, Peelor FF 3rd, Nguyen HVM, Richardson A, Choi S, Miller BF, Wanagat J. Age-induced changes in skeletal muscle mitochondrial DNA synthesis, quantity, and quality in genetically unique rats. Geroscience, 2024 September, PMID: 39312152

Chucair-Elliott AJ, Pham K, Cleuren ACA, Schafer CM, Griffin CT, Ocanas SR, Freeman WM, Elliott MH. Comparative Analysis of In vivo Endothelial Cell Translatomes Across Central Nervous System Vascular Beds. Exp Eye Res:110101, 2024 September, PMID: 39303842, PMCID: PMC11532013

Pollalis D, Nair GKG, Leung J, Bloemhof CM, Bailey JK, Pennington BO, Kelly KR, Khan AI, Yeh AK, Sundaram KS, Clegg DO, Peng CC, Xu L, Georgescu C, Wren JD, Lee SY. Dynamics of microRNA secreted via extracellular vesicles during the maturation of embryonic stem cell-derived retinal pigment epithelium. J Extracell Biol 3:e70001, 2024 September, PMID: 39281021, PMCID: PMC11393772

Huang KT, Wagner LE, Takano T, Lin XX, Bagavant H, Deshmukh U, Yule DI. Dysregulated Ca(2 ) signaling, fluid secretion, and mitochondrial function in a mouse model of early Sjögren's disease. Elife 13, 2024 September, PMID: 39259200, PMCID: PMC11390111

Das S, Varshney R, Farriester JW, Kyere-Davies G, Martinez AE, Hill K, Kinter M, Mullen GP, Nagareddy PR, Rudolph MC. NR2F2 Reactivation in Early-life Adipocyte Stem-like Cells Rescues Adipocyte Mitochondrial Oxidation. bioRxiv, 2024 September, PMID: 39314382, PMCID: PMC11419096

Sharpe AL, Liter LR, Donohue D, Carter KA, Vangeneugden P, Weaver S, Stout MB, Beckstead MJ. Aged mice exhibit faster acquisition of intravenous opioid self-administration with variable effects on intake. bioRxiv, 2024 September, PMID: 39282417, PMCID: PMC11398421

Kemna RE, Kueck PJ, Blankenship A, John CS, Johnson CN, Green ZD, Chamberlain T, Thyfault JP, Mahnken JD, Miller BF, Morris JK. Methods to characterize lactate turnover in aging and Alzheimer's disease; The LEAN study. Contemp Clin Trials:107682, 2024 September, PMID: 39236780

Kim H, Ranjit R, Claflin DR, Georgescu C, Wren JD, Brooks SV, Miller BF, Ahn B. Unacylated Ghrelin Protects Against Age-Related Loss of Muscle Mass and Contractile Dysfunction in Skeletal Muscle. Aging Cell:e14323, 2024 September, PMID: 39223708

Ma X, Wu W, Hara M, Zhou J, Panzarin C, Schafer CM, Griffin CT, Cai J, Ma JX, Takahashi Y. Deficient RPE mitochondrial energetics leads to subretinal fibrosis in age-related neovascular macular degeneration. Commun Biol 7:1075, 2024 September, PMID: 39223298, PMCID: PMC11369096

Scofield RH, Lewis VM. Is X chromosome inactivation a cause or effect of SLE? Nat Rev Rheumatol, 2024 September, PMID: 39223392

Bergwell M, Park J, Kirkland JG. Differential modulation of polycomb-associated histone marks by cBAF, pBAF, and gBAF complexes. Life Sci Alliance 7, 2024 August, PMID: 39209535, PMCID: PMC11361369

Nasuhidehnavi A, Zarzycka W, Górecki I, Chiao YA, Lee CF. Emerging interactions between mitochondria and NAD( ) metabolism in cardiometabolic diseases. Trends Endocrinol Metab, 2024 August, PMID: 39198117

Banks E, Francis V, Lin SJ, Kharfallah F, Fonov V, Lévesque M, Han C, Kulasekaran G, Tuznik M, Bayati A, Al-Khater R, Alkuraya FS, Argyriou L, Babaei M, Bahlo M, Bakhshoodeh B, Barr E, Bartik L, Bassiony M, Bertrand M, Braun D, Buchert R, Budetta M, Cadieux-Dion M, Calame DG, Cope H, Cushing D, Efthymiou S, Elmaksoud MA, El Said HG, Froukh T, Gill HK, Gleeson JG, Gogoll L, Goh ES, Gowda VK, Haack TB, Hashem MO, Hauser S, Hoffman TL, Hogue JS, Hosokawa A, Houlden H, Huang K, Huynh S, Karimiani EG, Kaulfuß S, Korenke GC, Kritzer A, Lee H, Lupski JR, Marco EJ, McWalter K, Minassian A, Minassian BA, Murphy D, Neira-Fresneda J, Northrup H, Nyaga DM, Oehl-Jaschkowitz B, Osmond M, Person R, Pehlivan D, Petree C, Sadleir LG, Saunders C, Schoels L, Shashi V, Spillmann RC, Srinivasan VM, Torbati PN, Tos T, Undiagnosed Diseases Network, Zaki MS, Zhou D, Zweier C, Trempe JF, Durcan TM, Gan-Or Z, Avoli M, Alves C, Varshney GK, Maroofian R, Rudko DA, McPherson PS. Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy. Nat Commun 15:7239, 2024 August, PMID: 39174524, PMCID: PMC11341845

Cordeiro B, Ahn JJ, Gawde S, Ucciferri C, Alvarez-Sanchez N, Revelo XS, Stickle N, Massey K, Brooks DG, Guthridge JM, Pardo G, Winer DA, Axtell RC, Dunn SE. Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females. Cell Metab, 2024 August, PMID: 39168127, PMCID: PMC11463735

Lawrence S, Scofield RH. Post traumatic stress disorder associated hypothalamic-pituitary-adrenal axis dysregulation and physical illness. Brain Behav Immun Health 41:100849, 2024 August, PMID: 39280087, PMCID: PMC11401111

Sok SPM, Pipkin K, Popescu NI, Reidy M, Li B, Van Remmen H, Kinter M, Sun XH, Fan Z, Zhao M. Gpx4 Regulates Invariant NKT Cell Homeostasis and Function by Preventing Lipid Peroxidation and Ferroptosis. J Immunol, 2024 August, PMID: 39158281, PMCID: PMC11408103

Puy C, Moellmer SA, Pang J, Vu H, Melrose A, Lorentz CU, Tucker EI, Shatzel JJ, Keshari RS, Lupu F, Gailani D, McCarty OJT. Coagulation factor XI regulates endothelial cell permeability and barrier function in vitro and in vivo. Blood, 2024 August, PMID: 39158072

Hines MR, Gomez-Contreras PC, Liman S, Wilson AM, Lu KJ, O'Neill JA, Fisher JS, Fredericks DC, Wagner BA, Buettner GR, Van Remmen H, Coleman MC. A reciprocal relationship between mitochondria and lipid peroxidation determines the chondrocyte intracellular redox environment. Redox Biol 75:103306, 2024 August, PMID: 39133964, PMCID: PMC11366903

Sathiaseelan R, Isola JVV, Santín-Márquez R, Adekunbi D, Fornalik M, Salmon AB, Stout MB. A pilot study evaluating dosing tolerability of 17α-estradiol in male common marmosets (Callithrix jacchus). Geroscience, 2024 August, PMID: 39107620

Iannitelli AF, Hassenein L, Mulvey B, Blankenship HE, Liles LC, Sharpe AL, Pare JF, Segal A, Sloan SA, Martinowich K, McCann KE, Dougherty JD, Smith Y, Beckstead MJ, Weinshenker D. Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus. bioRxiv, 2024 August, PMID: 36945637, PMCID: PMC10028911

Zahoor I, Pan G, Cerghet M, Elbayoumi T, Mao-Draayer Y, Giri S, Palaniyandi SS. Current understanding of cardiovascular autonomic dysfunction in multiple sclerosis. Heliyon 10:e35753, 2024 August, PMID: 39170118, PMCID: PMC11337049

Riecan M, Domanska V, Lupu C, Patel M, Vondrackova M, Rossmeisl M, Saghatelian A, Lupu F, Kuda O. Tissue-specific sex-dependent difference in the metabolism of fatty acid esters of hydroxy fatty acids. Biochim Biophys Acta Mol Cell Biol Lipids:159543, 2024 August, PMID: 39097081

Tandon I, Woessner A, Ferreira LA, Shamblin C, Vaca-Diez G, Walls A, Kuczwara P, Applequist A, Nascimento DF, Tandon S, Kim JW, Rausch M, Timek T, Padala M, Kinter MT, Province D, Byrum SD, Quinn KP, Balachandran K. A Three-Dimensional Valve-on-Chip Microphysiological System Implicates Cell Cycle Progression, Cholesterol Metabolism and Protein Homeostasis in Early Calcific Aortic Valve Disease Progression. Acta Biomater, 2024 July, PMID: 39084496

Hense JD, Garcia DN, Zanini BM, Barreto MM, Perreira GC, Isola JVV, de Brito C, Fornalik M, Mondal SA, Ávila BM, Oliveira TL, Rice HC, Lacy CI, Vaucher RA, Mason JB, Masternak MM, Stout MB, Schneider A. MASLD does not affect fertility and senolytics fail to prevent MASLD progression in male mice. Sci Rep 14:17332, 2024 July, PMID: 39068167, PMCID: PMC11283523

Deberneh HM, Taylor ME, Borowik AK, Miyagi M, Miller BF, Sadygov RG. Numbers of Exchangeable Hydrogens from LC-MS Data of Heavy Water Metabolically Labeled Samples. J Am Soc Mass Spectrom, 2024 July, PMID: 39057601

Hense JD, Isola JVV, Garcia DN, Magalhães LS, Masternak MM, Stout MB, Schneider A. The role of cellular senescence in ovarian aging. NPJ Aging 10:35, 2024 July, PMID: 39033161, PMCID: PMC11271274

Szybowska PE, Nasuhidehnavi A, Lee CF. Heartbreak to Immune Breakdown: myocardial infarction is causing thymic injury mediated by activation of the hypothalamus-pituitary-adrenal axis. Am J Physiol Heart Circ Physiol, 2024 July, PMID: 39028278

Xia L. Gasdermin D and TMA. Blood 144:247-248, 2024 July, PMID: 39023873, PMCID: PMC11302444

Davis MJ, Castorena-Gonzalez JA, Li M, Zawieja SD, Simon AM, Geng X, Srinivasan RS. Connexin45 (GJC1) is expressed in mouse lymphatic endothelium and required for normal lymphatic valve function. JCI Insight, 2024 July, PMID: 39074069, PMCID: PMC11343601

Schenk S, Sagendorf TJ, Many GM, Lira AK, de Sousa LGO, Bae D, Cicha M, Kramer KS, Muehlbauer M, Hevener AL, Rector RS, Thyfault JP, Williams JP, Goodyear LJ, Esser KA, Newgard CB, Bodine SC, MoTrPAC Study Group. Physiological Adaptations to Progressive Endurance Exercise Training in Adult and Aged Rats: Insights from the Molecular Transducers of Physical Activity Consortium (MoTrPAC). Function (Oxf) 5, 2024 July, PMID: 38984994, PMCID: PMC11245678

Wood TWP, Henriques WS, Cullen HB, Romero M, Blengini CS, Sarathy S, Sorkin J, Bekele H, Jin C, Kim S, Chemiakine A, Khondker RC, Isola JVV, Stout MB, Gennarino VA, Mogessie B, Jain D, Schindler K, Suh Y, Wiedenheft B, Berchowitz LE. The retrotransposon-derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity. Res Sq, 2024 July, PMID: 39041030, PMCID: PMC11261967

Shan X, Rathore S, Kniffen D, Gao L, Nitin, Letef CL, Shi H, Ghosh S, Zandberg W, Xia L, Bergstrom KSB. Ablation of intestinal epithelial sialylation predisposes to acute and chronic intestinal inflammation in mice. Cell Mol Gastroenterol Hepatol:101378, 2024 July, PMID: 38992465, PMCID: PMC11459652

Casares-Marfil D, Martínez-Bueno M, Borghi MO, Pons-Estel G, PRECISESADS Clinical Consortium, Reales G, Zuo Y, Espinosa G, Radstake T, van den Hoogen LL, Wallace C, Guthridge J, James JA, Cervera R, Luigi Meroni P, Martin J, Knight JS, Alarcón-Riquelme ME, Sawalha AH. A genome-wide association study suggests new susceptibility loci for primary antiphospholipid syndrome. Arthritis Rheumatol, 2024 July, PMID: 38973605, PMCID: PMC11521773

Ma H, Stanford D, Freeman WM, Ding XQ. Transcriptomic Analysis Reveals That Excessive Thyroid Hormone Signaling Impairs Phototransduction and Mitochondrial Bioenergetics and Induces Cellular Stress in Mouse Cone Photoreceptors. Int J Mol Sci 25, 2024 July, PMID: 39000540, PMCID: PMC11242393

Higgs MH, Beckstead MJ. Impact of unitary synaptic inhibition on spike timing in ventral tegmental area dopamine neurons. eNeuro, 2024 July, PMID: 38969500, PMCID: PMC11287791

Fava A, Wagner CA, Guthridge CJ, Kheir J, Macwana S, DeJager W, Gross T, Izmirly P, Belmont HM, Diamond B, Davidson A, Utz PJ, Weisman MH, Magder LS, Accelerating Medicines Partnership (AMP) RA/SLE Network, Guthridge JM, Petri M, Buyon J, James JA. Association of autoantibody concentrations and trajectories with lupus nephritis histological features and treatment response. Arthritis Rheumatol, 2024 July, PMID: 38962936, PMCID: PMC11521769

Qin W, Liang F, Lin SJ, Petree C, Huang K, Zhang Y, Li L, Varshney P, Mourrain P, Liu Y, Varshney GK. ABE-ultramax for high-efficiency biallelic adenine base editing in zebrafish. Nat Commun 15:5613, 2024 July, PMID: 38965236, PMCID: PMC11224239

Montgomery TL, Wang Q, Mirza A, Dwyer D, Wu Q, Dowling CA, Martens JWS, Yang J, Krementsov DN, Mao-Draayer Y. Identification of commensal gut microbiota signatures as predictors of clinical severity and disease progression in multiple sclerosis. Sci Rep 14:15292, 2024 July, PMID: 38961134, PMCID: PMC11222390

Gawde S, Siebert N, Ruprecht K, Kumar G, Ko RM, Massey K, Guthridge JM, Mao-Draayer Y, Schindler P, Hastermann M, Pardo G, Paul F, Axtell RC. Serum Proteomics Distinguish Subtypes of NMO Spectrum Disorder and MOG Antibody-Associated Disease and Highlight Effects of B-Cell Depletion. Neurol Neuroimmunol Neuroinflamm 11:e200268, 2024 July, PMID: 38885457, PMCID: PMC11186702

Ippolito GMR, Palanjian RR, Mao-Draayer Y, Capizzano A, Barboglio-Romo P, Clemens JQ, Gupta P, Dunn R, O'Dell D, Daignault-Newton S, Van Til M, Cameron AP, Stoffel JT. A Prospective Observational Study of Posterior Tibial Nerve Stimulation in Multiple Sclerosis. Int Urogynecol J, 2024 June, PMID: 38942931

Merrill JT, Tanaka Y, D'Cruz D, Vila-Rivera K, Siri D, Zeng X, Saxena A, Aringer M, D'Silva KM, Cheng L, Mohamed MF, Siovitz L, Bhatnagar S, Gaudreau MC, Doan TT, Friedman A. Efficacy and Safety of Upadacitinib or Elsubrutinib Alone or in Combination for Systemic Lupus Erythematosus: A Phase 2 Randomized Controlled Trial. Arthritis Rheumatol, 2024 June, PMID: 38923871

Bubak MP, Davidyan A, O'Reilly CL, Mondal SA, Keast J, Doidge SM, Borowik AK, Taylor ME, Volovičeva E, Kinter MT, Britton SL, Koch LG, Stout MB, Lewis TL Jr, Miller BF. Metformin treatment results in distinctive skeletal muscle mitochondrial remodeling in rats with different intrinsic aerobic capacities. Aging Cell:e14235, 2024 June, PMID: 38923664, PMCID: PMC11488331

Kobak KA, Batushansky A, Jopkiewicz A, Peelor FF 3rd, Kinter MT, Miller BF, Griffin TM. Effect of biological sex and short-term high-fat diet on cellular proliferation, ribosomal biogenesis, and targeted protein abundance in murine articular cartilage. Osteoarthr Cartil Open 6:100495, 2024 June, PMID: 39040627, PMCID: PMC11260562

Shi H, Song J, Gao L, Shan X, Panicker SR, Yao L, McDaniel M, Zhou M, McGee S, Zhong H, Griffin CT, Xia L, Shao B. Deletion of Talin1 in Myeloid Cells Facilitates Atherosclerosis in Mice. Arterioscler Thromb Vasc Biol, 2024 June, PMID: 38899470

Cox JEJ, Pham KD, Keck AW, Wright Z, Thomas MA, Freeman WM, Ocañas SR. Flow Cytometry Analysis of Microglial Phenotypes in the Murine Brain During Aging and Disease. Bio Protoc 14:e5018, 2024 June, PMID: 38948260, PMCID: PMC11211077

Wu ML, Wheeler K, Silasi R, Lupu F, Griffin CT. Endothelial Chromatin-Remodeling Enzymes Regulate the Production of Critical ECM Components During Murine Lung Development. Arterioscler Thromb Vasc Biol, 2024 June, PMID: 38868942

Nyúl-Tóth Á, Negri S, Sanford M, Jiang R, Patai R, Budda M, Petersen B, Pinckard J, Chandragiri SS, Shi H, Reyff Z, Ballard C, Gulej R, Csik B, Ferrier J, Balasubramanian P, Yabluchanskiy A, Cleuren A, Conley S, Ungvari Z, Csiszar A, Tarantini S. Novel intravital approaches to quantify deep vascular structure and perfusion in the aging mouse brain using ultrasound localization microscopy (ULM). J Cereb Blood Flow Metab:271678X241260526, 2024 June, PMID: 38867576, PMCID: PMC11542130

Rajala R, Cleuren ACA, Griffin CT. Acetaminophen Overdose Reveals Protease-Activated Receptor 4 as a Low-Expressing but Potent Receptor on the Hepatic Endothelium. bioRxiv, 2024 June, PMID: 38895465, PMCID: PMC11185779

Kang S, Ko EY, Andrews AE, Shin JE, Nance KJ, Barman PK, Heeger PS, Freeman WM, Benayoun BA, Goodridge HS. Microglia undergo sex-dimorphic transcriptional and metabolic rewiring during aging. J Neuroinflammation 21:150, 2024 June, PMID: 38840206, PMCID: PMC11155174

Anderson E, Powell M, Yang E, Kar A, Leung TM, Sison C, Steinberg R, Mims R, Choudhury A, Espinosa C, Zelmanovich J, Okoye NC, Choi EJ, Marder G, Narain S, Gregersen PK, Mackay M, Diamond B, Levy T, Zanos TP, Khosroshahi A, Sanz I, Luning Prak ET, Bar-Or A, Merrill J, Arriens C, Pardo G, Guthridge J, James J, Payne A, Utz PJ, Boss JM, Aranow C, Davidson A. Factors associated with immune responses to SARS-CoV-2 vaccination in autoimmune disease individuals. JCI Insight, 2024 June, PMID: 38833310, PMCID: PMC11383356

Negri S, Sanford M, Reyff Z, Ballard C, Nyul-Toth A, Gulej R, Brown J, O'Reilly C, Van Remmen H, Csiszar A, Ungvari Z, Tarantini S. Transcriptomic signatures of time-restricted feeding (TRF) in cerebrovascular aging and cognitive health. Vascul Pharmacol 155:107338, 2024 June, PMID: 38985616

Papinska JA, Durślewicz J, Bagavant H, Deshmukh US. Deleting Mitochondrial Superoxide Dismutase 2 in Salivary Gland Ductal Epithelial Cells Recapitulates Non-Sjögren's Sicca Syndrome. Int J Mol Sci 25, 2024 May, PMID: 38892170, PMCID: PMC11172772

Morand EF, Pike M, Merrill J, F van Vollenhoven R, Werth VP, Hobar C, Delev N, Shah V, Sharkey B, Wegman T, Catlett I, Banerjee S, Singhal S. Plain Language Summary of the PAISLEY study: deucravacitinib as a treatment for people with systemic lupus erythematosus. Expert Opin Investig Drugs:1-11, 2024 May, PMID: 38807572

Keener R, Chhetri SB, Connelly CJ, Taub MA, Conomos MP, Weinstock J, Ni B, Strober B, Aslibekyan S, Auer PL, Barwick L, Becker LC, Blangero J, Bleecker ER, Brody JA, Cade BE, Celedon JC, Chang YC, Cupples LA, Custer B, Freedman BI, Gladwin MT, Heckbert SR, Hou L, Irvin MR, Isasi CR, Johnsen JM, Kenny EE, Kooperberg C, Minster RL, Naseri T, Viali S, Nekhai S, Pankratz N, Peyser PA, Taylor KD, Telen MJ, Wu B, Yanek LR, Yang IV, Albert C, Arnett DK, Ashley-Koch AE, Barnes KC, Bis JC, Blackwell TW, Boerwinkle E, Burchard EG, Carson AP, Chen Z, Chen YI, Darbar D, de Andrade M, Ellinor PT, Fornage M, Gelb BD, Gilliland FD, He J, Islam T, Kaab S, Kardia SLR, Kelly S, Konkle BA, Kumar R, Loos RJF, Martinez FD, McGarvey ST, Meyers DA, Mitchell BD, Montgomery CG, North KE, Palmer ND, Peralta JM, Raby BA, Redline S, Rich SS, Roden D, Rotter JI, Ruczinski I, Schwartz D, Sciurba F, Shoemaker MB, Silverman EK, Sinner MF, Smith NL, Smith AV, Tiwari HK, Vasan RS, Weiss ST, Williams LK, Zhang Y, Ziv E, Raffield LM, Reiner AP, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology and Hemostasis Working Group, TOPMed Structural Variation Working Group, Arvanitis M, Greider CW, Mathias RA, Battle A. Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes. Nat Commun 15:4417, 2024 May, PMID: 38789417, PMCID: PMC11126610

Camon C, Prescott M, Neyt C, Decourt C, Stout MB, Campbell RE, Garratt M. Systemic metabolic benefits of 17α-estradiol are not exclusively mediated by ERα in glutamatergic or GABAergic neurons. Geroscience, 2024 May, PMID: 38776045, PMCID: PMC11493872

Barber MRW, Ugarte-Gil MF, Hanly JG, Urowitz MB, St-Pierre Y, Gordon C, Bae SC, Romero-Diaz J, Sanchez-Guerrero J, Bernatsky S, Wallace DJ, Isenberg DA, Rahman A, Merrill JT, Fortin PR, Gladman DD, Bruce IN, Petri M, Ginzler EM, Dooley MA, Ramsey-Goldman R, Manzi S, Jönsen A, van Vollenhoven RF, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, Kalunian KC, Jacobsen S, Peschken CA, Kamen DL, Askanase A, Pons-Estel BA, Cardwell FS, Alarcón GS, Clarke AE. Remission and low disease activity are associated with lower healthcare costs: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort. Ann Rheum Dis, 2024 May, PMID: 38754981

Milan M, Brown J, O'Reilly CL, Bubak MP, Negri S, Balasubramanian P, Dhanekula AS, Pharaoh G, Reyff Z, Ballard C, Shi H, Yabluchanskiy A, Rudolph MC, Ungvari Z, Marcinek DJ, Miller BF, Van Remmen H, Tarantini S. Time-restricted feeding improves aortic endothelial relaxation by enhancing mitochondrial function and attenuating oxidative stress in aged mice. Redox Biol 73:103189, 2024 May, PMID: 38788541, PMCID: PMC11140804

Lincoln MR, Connally N, Axisa PP, Gasperi C, Mitrovic M, van Heel D, Wijmenga C, Withoff S, Jonkers IH, Padyukov L, International Multiple Sclerosis Genetics Consortium, Rich SS, Graham RR, Gaffney PM, Langefeld CD, Vyse TJ, Hafler DA, Chun S, Sunyaev SR, Cotsapas C. Genetic mapping across autoimmune diseases reveals shared associations and mechanisms. Nat Genet, 2024 May, PMID: 38741015

Simeroth S, Yu P. The role of lymphatic endothelial cell metabolism in lymphangiogenesis and disease. Front Cardiovasc Med 11:1392816, 2024 May, PMID: 38798921, PMCID: PMC11119333

Mian Y, Wang L, Keikhosravi A, Guo K, Misteli T, Arda HE, Finn EH. Cell type- and transcription-independent spatial proximity between enhancers and promoters. Mol Biol Cell:mbcE24020082, 2024 May, PMID: 38717453, PMCID: PMC11244156

Chucair-Elliott AJ, Ocañas SR, Pham K, Machalinski A, Plafker S, Stout MB, Elliott MH, Freeman WM. Age- and sex- divergent translatomic responses of the mouse retinal pigmented epithelium. Neurobiol Aging 140:41-59, 2024 May, PMID: 38723422, PMCID: PMC11173338

Many GM, Sanford JA, Sagendorf TJ, Hou Z, Nigro P, Whytock KL, Amar D, Caputo T, Gay NR, Gaul DA, Hirshman MF, Jimenez-Morales D, Lindholm ME, Muehlbauer MJ, Vamvini M, Bergman BC, Fernández FM, Goodyear LJ, Hevener AL, Ortlund EA, Sparks LM, Xia A, Adkins JN, Bodine SC, Newgard CB, Schenk S, MoTrPAC Study Group. Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue. Nat Metab, 2024 May, PMID: 38693320, PMCID: PMC11132991

Isola JVV, Hense JD, Osorio CAP, Biswas S, Alberola-Ila J, Ocanas SR, Schneider A, Stout MB. Inflammation, immune cells, and cellular senescence in the aging ovary. Reproduction, 2024 May, PMID: 38744316, PMCID: PMC11301429

Zivadinov R, Bergsland N, Jakimovski D, Weinstock-Guttman B, Lorefice L, Schoonheim MM, Morrow SA, Ann Picone M, Pardo G, Zarif M, Gudesblatt M, Nicholas JA, Smith A, Hunter S, Newman S, AbdelRazek MA, Hoti I, Riolo J, Silva D, Fuchs TA, Dwyer MG, Hb Benedict R. Thalamic atrophy and dysconnectivity are associated with cognitive impairment in a multi-center, clinical routine, real-word study of people with relapsing-remitting multiple sclerosis. Neuroimage Clin 42:103609, 2024 April, PMID: 38718640, PMCID: PMC11098945

Bagavant H, Durslewicz J, Pyclik M, Makuch M, Papinska JA, Deshmukh US. Age-associated B cell infiltration in salivary glands represents a hallmark of Sjögren's-like disease in aging mice. Geroscience, 2024 April, PMID: 38656650, PMCID: PMC11493885

Evatt JM, Sadli AD, Rapacz BK, Chuong HH, Meyer RE, Ridenour JB, Donczew R, Dawson DS. Centromere pairing enables correct segregation of meiotic chromosomes. Curr Biol, 2024 April, PMID: 38670094, PMCID: PMC11111343

Brown CA, Wren JD. AutoGDC: A Python Package for DNA Methylation and Transcription Meta-Analyses. bioRxiv, 2024 April, PMID: 38659836, PMCID: PMC11042378

Amar D, Gay NR, Jimenez-Morales D, Jean Beltran PM, Ramaker ME, Raja AN, Zhao B, Sun Y, Marwaha S, Gaul DA, Hershman SG, Ferrasse A, Xia A, Lanza I, Fernández FM, Montgomery SB, Hevener AL, Ashley EA, Walsh MJ, Sparks LM, Burant CF, Rector RS, Thyfault J, Wheeler MT, Goodpaster BH, Coen PM, Schenk S, Bodine SC, Lindholm ME, MoTrPAC Study Group. The mitochondrial multi-omic response to exercise training across rat tissues. Cell Metab, 2024 April, PMID: 38701776, PMCID: PMC11152996

Chakraborty P, Niewiadomska M, Farhat K, Morris L, Whyte S, Humphries KM, Stavrakis S. Effect of Low-Level Tragus Stimulation on Cardiac Metabolism in Heart Failure with Preserved Ejection Fraction: A Transcriptomics-Based Analysis. Int J Mol Sci 25, 2024 April, PMID: 38673896, PMCID: PMC11050145

Rankin BD, Rankin S. The MCM2-7 Complex: Roles beyond DNA Unwinding. Biology (Basel) 13, 2024 April, PMID: 38666870, PMCID: PMC11048021

Krustev E, Hanly JG, Chin R, Buhler KA, Urowitz MB, Gordon C, Bae SC, Romero-Diaz J, Sánchez-Guerrero J, Bernatsky S, Wallace DJ, Isenberg D, Rahman A, Merrill JT, Fortin PR, Gladman DD, Bruce IN, Petri MA, Ginzler EM, Dooley MA, Ramsey-Goldman R, Manzi S, Jönsen A, Alarcón GS, van Vollenhoven RF, Aranow C, Mackay M, Ruiz-Irastorza G, Lim S, Inanc M, Kalunian KC, Jacobsen S, Peschken CA, Kamen DL, Askenase A, Buyon J, Fritzler MJ, Clarke AE, Choi MY. Anti-KIF20B autoantibodies are associated with cranial neuropathy in systemic lupus erythematosus. Lupus Sci Med 11, 2024 April, PMID: 38599670, PMCID: PMC11015279

Aleman M, Arepally GM, Baglin T, Buitrago L, Davizon-Castillo P, Dayal S, Flick MJ, Gerber G, Hisada Y, Kolev K, O'Loghlen A, Rezaie AR, Sparkenbaugh EM, Stavrou EX, Ünlü B, Vercellotti GM. Coagulation and platelet biology at the intersection of health and disease: illustrated capsules of the 11th Symposium on Hemostasis at the University of North Carolina. Res Pract Thromb Haemost 8:102395, 2024 April, PMID: 38699410, PMCID: PMC11063502

Harold KM, Matsuzaki S, Pranay A, Loveland BL, Batushansky A, Mendez Garcia MF, Eyster C, Stavrakis S, Chiao YA, Kinter M, Humphries KM. Loss of Cardiac PFKFB2 Drives Metabolic, Functional, and Electrophysiological Remodeling in the Heart. J Am Heart Assoc 13:e033676, 2024 April, PMID: 38533937, PMCID: PMC11179765

Chen J, Ding Y, Jiang C, Qu R, Wren JD, Georgescu C, Wang X, Reuter DN, Liu B, Giles CB, Mayr CH, Schiller HB, Dai J, Stipp CS, Subramaniyan B, Wang J, Zuo H, Huang C, Fung KM, Rice HC, Sonnenberg A, Wu D, Walters MS, Zhao YY, Kanie T, Hays FA, Papin JF, Wang DW, Zhang XA. CD151 Maintains Endolysosomal Protein Quality to Inhibit Vascular Inflammation. Circ Res, 2024 April, PMID: 38557119, PMCID: PMC11081830

Noh JY, Farhataziz N, Kinter MT, Yan X, Sun Y. Colonic Dysregulation of Major Metabolic Pathways in Experimental Ulcerative Colitis. Metabolites 14, 2024 March, PMID: 38668322, PMCID: PMC11052278

Carlucci PM, Preisinger K, Deonaraine KK, Zaminski D, Dall'Era M, Gold HT, Kalunian K, Fava A, Belmont HM, Wu M, Putterman C, Anolik J, Barnas JL, Furie R, Diamond B, Davidson A, Wofsy D, Kamen D, James JA, Guthridge JM, Apruzzese W, Rao D, Weisman MH, Accelerating Medicines Partnership in RA/SLE Network, Izmirly PM, Buyon J, Petri M. Extrarenal symptoms associate with worse quality of life in patients enrolled in the AMP RA/SLE Lupus Nephritis Network. Rheumatology (Oxford), 2024 March, PMID: 38530774

Komaravolu RK, Mehta-D'souza P, Conner T, Allen M, Lumry J, Batushansky A, Pezant NP, Montgomery CG, Griffin TM. Sex-specific effects of injury and beta-adrenergic activation on metabolic and inflammatory mediators in a murine model of post-traumatic osteoarthritis. Osteoarthritis Cartilage, 2024 March, PMID: 38527663, PMCID: PMC11330734

Hatch CJ, Piombo SD, Fang JS, Gach JS, Ewald ML, Van Trigt WK, Coon BG, Tong JM, Forthal DN, Hughes CCW. SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system. Front Cardiovasc Med 11:1360364, 2024 March, PMID: 38576426, PMCID: PMC10991679

Xu H, Piekarz KM, Brown JL, Bhaskaran S, Smith N, Towner RA, Van Remmen H. Neuroprotective treatment with the nitrone compound OKN-007 mitigates age-related muscle weakness in aging mice. Geroscience, 2024 March, PMID: 38512579, PMCID: PMC11336152

Huang KT, Wagner LE, Takano T, Lin XX, Bagavant H, Deshmukh U, Yule DI. Dysregulated Ca(2 ) signaling, fluid secretion, and mitochondrial function in a mouse model of early Sjögren's syndrome. bioRxiv, 2024 March, PMID: 38562738, PMCID: PMC10983907

Palakshappa JA, Batt JAE, Bodine SC, Connolly BA, Doles J, Falvey JR, Ferrante LE, Files DC, Harhay MO, Harrell K, Hippensteel JA, Iwashyna TJ, Jackson JC, Lane-Fall MB, Monje M, Moss M, Needham DM, Semler MW, Lahiri S, Larsson L, Sevin CM, Sharshar T, Singer B, Stevens T, Taylor SP, Gomez CR, Zhou G, Girard TD, Hough CL. Tackling Brain and Muscle Dysfunction in Acute Respiratory Distress Syndrome Survivors: National Heart, Lung, and Blood Institute Workshop Report. Am J Respir Crit Care Med, 2024 March, PMID: 38477657, PMCID: PMC11146564

Yang J, Zhu L, Pan H, Ueharu H, Toda M, Yang Q, Hallett SA, Olson LE, Mishina Y. A BMP-controlled metabolic-epigenetic signaling cascade directs midfacial morphogenesis. J Clin Invest, 2024 March, PMID: 38466355, PMCID: PMC11014657

Cross AH, Gelfand JM, Thebault S, Bennett JL, von Büdingen HC, Cameron B, Carruthers R, Edwards K, Fallis R, Gerstein R, Giacomini PS, Greenberg B, Hafler DA, Ionete C, Kaunzner UW, Kodama L, Lock C, Longbrake EE, Musch B, Pardo G, Piehl F, Weber MS, Yuen S, Ziemssen T, Bose G, Freedman MS, Anania VG, Ramesh A, Winger RC, Jia X, Herman A, Harp C, Bar-Or A. Emerging Cerebrospinal Fluid Biomarkers of Disease Activity and Progression in Multiple Sclerosis. JAMA Neurol, 2024 March, PMID: 38466277, PMCID: PMC10928543

Zuo B, Yang F, Huang L, Han J, Li T, Ma Z, Cao L, Li Y, Bai X, Jiang M, He Y, Xia L. Endothelial Slc35a1 deficiency causes loss of LSEC identity and exacerbates neonatal lipid deposition in the liver in mice. Cell Mol Gastroenterol Hepatol, 2024 March, PMID: 38467191, PMCID: PMC11061248

Virga DM, Hamilton S, Osei B, Morgan A, Kneis P, Zamponi E, Park NJ, Hewitt VL, Zhang D, Gonzalez KC, Russell FM, Grahame Hardie D, Prudent J, Bloss E, Losonczy A, Polleux F, Lewis TL Jr. Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo. Nat Commun 15:2142, 2024 March, PMID: 38459070, PMCID: PMC10923867

Winnicki MJ, Brown CA, Porter HL, Giles CB, Wren JD. BioVDB: biological vector database for high-throughput gene expression meta-analysis. Front Artif Intell 7:1366273, 2024 March, PMID: 38525301, PMCID: PMC10957786

Jog NR, Wagner CA, Aberle T, Chakravarty EF, Arriens C, Guthridge JM, James JA. Neutrophils isolated from systemic lupus erythematosus patients exhibit a distinct functional phenotype. Front Immunol 15:1339250, 2024 March, PMID: 38524128, PMCID: PMC10957542

Mytych JS, Pan Z, Lopez-Davis C, Redinger N, Lawrence C, Ziegler J, Popescu NI, James JA, Farris AD. Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3. Immunohorizons 8:269-280, 2024 March, PMID: 38517345, PMCID: PMC10985058

Stock AJ, Gonzalez Paredes P, de Almeida LP, Kosanke SD, Chetlur S, Budde H, Wakenight P, Zwingman TA, Rosen ABI, Allenspach EJ, Millen KJ, Buckner JH, Rawlings DJ, Gorman JA. The IFIH1-A946T risk variant promotes diabetes in a sex-dependent manner. Front Immunol 15:1349601, 2024 February, PMID: 38487540, PMCID: PMC10937421

Ohene-Marfo P, Nguyen HVM, Mohammed S, Thadathil N, Tran A, Nicklas EH, Wang D, Selvarani R, Farriester JW, Varshney R, Kinter M, Richardson A, Rudolph MC, Deepa SS. Non-Necroptotic Roles of MLKL in Diet-Induced Obesity, Liver Pathology, and Insulin Sensitivity: Insights from a High-Fat, High-Fructose, High-Cholesterol Diet Mouse Model. Int J Mol Sci 25, 2024 February, PMID: 38474061, PMCID: PMC10931720

Hinton A Jr, Katti P, Mungai M, Hall DD, Koval O, Shao J, Vue Z, Lopez EG, Rostami R, Neikirk K, Ponce J, Streeter J, Schickling B, Bacevac S, Grueter C, Marshall A, Beasley HK, Do Koo Y, Bodine SC, Nava NGR, Quintana AM, Song LS, Grumbach IM, Pereira RO, Glancy B, Abel ED. ATF4-dependent increase in mitochondrial-endoplasmic reticulum tethering following OPA1 deletion in skeletal muscle. J Cell Physiol, 2024 February, PMID: 38419397, PMCID: PMC11144302

Huang L, Kondo Y, Cao L, Han J, Li T, Zuo B, Yang F, Li Y, Ma Z, Bai X, Jiang M, Ruan C, Xia L. Novel GNE missense variants impair de novo sialylation and cause defective angiogenesis in the developing brain in mice. Blood Adv 8:991-1001, 2024 February, PMID: 38237079, PMCID: PMC10879683

Fu Y, Kelly JA, Gopalakrishnan J, Pelikan RC, Tessneer KL, Pasula S, Grundahl K, Murphy DA, Gaffney PM. Massively Parallel Reporter Assay Confirms Regulatory Potential of hQTLs and Reveals Important Variants in Lupus and Other Autoimmune Diseases. HGG Adv:100279, 2024 February, PMID: 38389303, PMCID: PMC10943488

Xiong Y, Kullberg S, Garman L, Pezant N, Ellinghaus D, Vasila V, Eklund A, Rybicki BA, Iannuzzi MC, Schreiber S, Müller-Quernheim J, Montgomery CG, Grunewald J, Padyukov L, Rivera NV. Corrigendum: Sex differences in the genetics of sarcoidosis across European and African ancestry populations. Front Med (Lausanne) 11:1382584, 2024 February, PMID: 38449888, PMCID: PMC10915398

Gurrea-Rubio M, Wang Q, Mills EA, Wu Q, Pitt D, Tsou PS, Fox DA, Mao-Draayer Y. Siponimod Attenuates Neuronal Cell Death Triggered by Neuroinflammation via NFκB and Mitochondrial Pathways. Int J Mol Sci 25, 2024 February, PMID: 38473703, PMCID: PMC10931690

Izmirly PM, Kim MY, Carlucci PM, Preisinger K, Cohen BZ, Deonaraine K, Zaminski D, Dall'Era M, Kalunian K, Fava A, Belmont HM, Wu M, Putterman C, Anolik J, Barnas JL, Diamond B, Davidson A, Wofsy D, Kamen D, James JA, Guthridge JM, Apruzzese W, Rao DA, Weisman MH, Accelerating Medicines Partnership in RA/SLE Network, Petri M, Buyon J, Furie R. Longitudinal patterns and predictors of response to standard-of-care therapy in lupus nephritis: data from the Accelerating Medicines Partnership Lupus Network. Arthritis Res Ther 26:54, 2024 February, PMID: 38378664, PMCID: PMC10877793

Fazel-Najafabadi M, Looger LL, Rallabandi HR, Nath SK. A multilayered post-GWAS analysis pipeline defines functional variants and target genes for systemic lupus erythematosus (SLE). Arthritis Rheumatol, 2024 February, PMID: 38369936, PMCID: PMC11213670

Singh MK, Rallabandi HR, Zhou XJ, Qi YY, Zhao ZZ, Gan T, Zhang H, Looger LL, Nath SK. KLF2 enhancer variant rs4808485 increases lupus risk by modulating inflammasome machinery and cellular homoeostasis. Ann Rheum Dis, 2024 February, PMID: 38373841, PMCID: PMC11168881

Hirabayashi Y, Lewis TL Jr, Du Y, Virga DM, Decker AM, Coceano G, Alvelid J, Paul MA, Hamilton S, Kneis P, Takahashi Y, Gaublomme JT, Testa I, Polleux F. Most axonal mitochondria in cortical pyramidal neurons lack mitochondrial DNA and consume ATP. bioRxiv, 2024 February, PMID: 38405915, PMCID: PMC10888904

Ziaei A, Solomon O, Casper TC, Waltz M, Weinstock-Guttman B, Aaen G, Wheeler Y, Graves J, Benson L, Gorman M, Rensel M, Mar S, Lotze T, Greenberg B, Chitnis T, Waldman AT, Krupp L, James JA, Hart J, Barcellos LF, Waubant E. Gene-environment interactions: Epstein-Barr virus infection and risk of pediatric-onset multiple sclerosis. Mult Scler:13524585231224685, 2024 February, PMID: 38332747, PMCID: PMC11093131

Noble TD, Sansam CG, Wittig KA, Majchrzycka B, Sansam CL. Cell Cycle-Dependent TICRR/TRESLIN and MTBP Chromatin Binding Mechanisms and Patterns. bioRxiv, 2024 February, PMID: 38370757, PMCID: PMC10871258

Deepa SS, Thadathil N, Corral J, Mohammed S, Pham S, Rose H, Kinter MT, Richardson A, Díaz-García CM. MLKL overexpression leads to Ca(2 ) and metabolic dyshomeostasis in a neuronal cell model. Cell Calcium 119:102854, 2024 February, PMID: 38430790, PMCID: PMC10990772

Banks E, Francis V, Lin SJ, Kharfallah F, Fonov V, Levesque M, Han C, Kulasekaran G, Tuznik M, Bayati A, Al-Khater R, Alkuraya FS, Argyriou L, Babaei M, Bahlo M, Bakhshoodeh B, Barr E, Bartik L, Bassiony M, Bertrand M, Braun D, Buchert R, Budetta M, Cadieux-Dion M, Calame D, Cope H, Cushing D, Efthymiou S, Elmaksoud MA, El Said HG, Froukh T, Gill HK, Gleeson JG, Gogoll L, Goh ES, Gowda VK, Haack TB, Hashem MO, Hauser S, Hoffman TL, Hogue JS, Hosokawa A, Houlden H, Huang K, Huynh S, Karimiani EG, Kaulfuß S, Korenke GC, Kritzer A, Lee H, Lupski JR, Marco EJ, McWalter K, Minassian A, Minassian BA, Murphy D, Neira-Fresneda J, Northrup H, Nyaga D, Oehl-Jaschkowitz B, Osmond M, Person R, Pehlivan D, Petree C, Sadleir LG, Saunders C, Schoels L, Shashi V, Spillman RC, Srinivasan VM, Torbati PN, Tos T, Undiagnosed Diseases Network, Zaki MS, Zhou D, Zweier C, Trempe JF, Durcan TM, Gan-Or Z, Avoli M, Alves C, Varshney GK, Maroofian R, Rudko DA, McPherson PS. Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy. medRxiv, 2024 January, PMID: 38352438, PMCID: PMC10863025

Veiga GB, Zanini BM, Garcia DN, Hense JD, Barreto MM, Isola JVV, Mondadori RG, Masternak MM, Stout MB, Schneider A. Effects of calorie, protein, and branched chain amino acid restriction on ovarian aging in mice. Reprod Biol 24:100856, 2024 January, PMID: 38295721, PMCID: PMC10978239

Chakravarty EF, Utset T, Kamen DL, Contreras G, McCune WJ, Aranow C, Kalunian K, Massarotti E, Clowse MEB, Rovin BH, Lim SS, Majithia V, Dall'Era M, Looney RJ, Erkan D, Saxena A, Olsen NJ, Ko K, Guthridge JM, Goldmuntz E, Springer J, D'Aveta C, Keyes-Elstein L, Barry B, Pinckney A, McNamara J, James JA. Mycophenolate mofetil withdrawal in patients with systemic lupus erythematosus: a multicentre, open-label, randomised controlled trial. Lancet Rheumatol, 2024 January, PMID: 38301682, PMCID: PMC10922882

Gurrea-Rubio M, Wu Q, Amin MA, Tsou PS, Campbell PL, Amarista CI, Ikari Y, Brodie WD, Mattichak MN, Muraoka S, Randon PM, Lind ME, Ruth JH, Mao-Draayer Y, Ding S, Shen X, Cooney LA, Lin F, Fox DA. Activation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells. Cancer Immunol Immunother 73:34, 2024 January, PMID: 38280067, PMCID: PMC10821976

Sherman MA, Noroozi Farhadi P, Pak K, Trieu EP, Sarkar K, Targoff IN, Neely ML, Mammen AL, Rider LG, Childhood Myositis Heterogeneity Collaborative Study Group. Myositis-associated autoantibodies in juvenile myositis are associated with refractory disease and mortality. Arthritis Rheumatol, 2024 January, PMID: 38272842, PMCID: PMC11136598

Fava A, Buyon J, Magder L, Hodgin J, Rosenberg A, Demeke DS, Rao DA, Arazi A, Celia AI, Putterman C, Anolik JH, Barnas J, Dall'Era M, Wofsy D, Furie R, Kamen D, Kalunian K, James JA, Guthridge J, Atta MG, Monroy Trujillo J, Fine D, Clancy R, Belmont HM, Izmirly P, Apruzzese W, Goldman D, Berthier CC, Hoover P, Hacohen N, Raychaudhuri S, Davidson A, Diamond B, Accelerating Medicines Partnership in RA/SLE network, Petri M. Urine proteomic signatures of histological class, activity, chronicity, and treatment response in lupus nephritis. JCI Insight 9, 2024 January, PMID: 38258904, PMCID: PMC10906224

Giri H, Biswas I, Rezaie AR. Thrombomodulin: A multifunctional receptor modulating the endothelial quiescence. J Thromb Haemost, 2024 January, PMID: 38266676, PMCID: PMC10960680

Larson KR, Jayakrishnan D, Soto Sauza KA, Goodson ML, Chaffin AT, Davidyan A, Pathak S, Fang Y, Gonzalez Magaña D, Miller BF, Ryan KK. FGF21 induces skeletal muscle atrophy and increases amino acids in female mice: a potential role for glucocorticoids. Endocrinology, 2024 January, PMID: 38244215, PMCID: PMC10849119

Borowik AK, Lawrence MM, Peelor FF 3rd, Piekarz KM, Crosswhite A, Richardson A, Miller BF, Van Remmen H, Brown JL. Senolytic treatment does not mitigate oxidative stress-induced muscle atrophy but improves muscle force generation in CuZn superoxide dismutase knockout mice. Geroscience, 2024 January, PMID: 38233728, PMCID: PMC11009189

Muñoz-Oreja M, Sandoval A, Bruland O, Perez-Rodriguez D, Fernandez-Pelayo U, de Arbina AL, Villar-Fernandez M, Hernández-Eguiazu H, Hernández I, Park Y, Goicoechea L, Pascual-Frías N, Garcia-Ruiz C, Fernandez-Checa J, Martí-Carrera I, Gil-Bea FJ, Hasan MT, Gegg ME, Bredrup C, Knappskog PM, Gereñu-Lopetegui G, Varhaug KN, Bindoff LA, Spinazzola A, Yoon WH, Holt IJ. Elevated cholesterol in ATAD3 mutants is a compensatory mechanism that leads to membrane cholesterol aggregation. Brain, 2024 January, PMID: 38242545, PMCID: PMC11068212

Isola JVV, Ocañas SR, Hubbart CR, Ko S, Mondal SA, Hense JD, Carter HNC, Schneider A, Kovats S, Alberola-Ila J, Freeman WM, Stout MB. A single-cell atlas of the aging mouse ovary. Nat Aging, 2024 January, PMID: 38200272, PMCID: PMC10798902

Bubak MP, Mann SN, Borowik AK, Pranay A, Batushansky A, Vieira de Sousa Neto I, Ali Mondal SA, Doidge SM, Davidyan A, Szczygiel MM, Peelor Iii FF, Rigsby S, Broomfield ME, Lacy CI, Rice HC, Stout MB, Miller BF. 17α-estradiol Alleviates High-Fat Diet-Induced Inflammatory and Metabolic Dysfunction in Skeletal Muscle of Male and Female Mice. Am J Physiol Endocrinol Metab, 2024 January, PMID: 38197793, PMCID: PMC11193529

Radhakrishna U, Sadhasivam S, Radhakrishnan R, Forray A, Muvvala SB, Metpally RP, Patel S, Rawal RM, Vishweswaraiah S, Bahado-Singh RO, Nath SK. Placental cytochrome P450 methylomes in infants exposed to prenatal opioids: exploring the effects of neonatal opioid withdrawal syndrome on health horizons. Front Genet 14:1292148, 2024 January, PMID: 38264209, PMCID: PMC10805101

Biswas I, Giri H, Panicker SR, Rezaie AR. Thrombomodulin Switches Signaling and Protease-Activated Receptor 1 Cleavage Specificity of Thrombin. Arterioscler Thromb Vasc Biol, 2024 January, PMID: 38174561, PMCID: PMC10922642

Boutagy NE, Gamez-Mendez A, Fowler JW, Zhang H, Chaube BK, Esplugues E, Lee S, Horikami D, Zhang J, Citrin KM, Singh AK, Coon BG, Suarez Y, Fernandez-Hernando C, Sessa WC. Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice. J Clin Invest, 2024 January, PMID: 38175710, PMCID: PMC10866653

de Almeida LP, Lee CY, Carbajal A, de Castro RO, Pezza RJ. Visualization and Quantification of Rapid Chromosome Movements at Early Stages of Mouse Meiosis. Methods Mol Biol 2818:171-177, 2024 January, PMID: 39126474

Carbajal A, Gryniuk I, de Castro RO, Pezza RJ. Efficient Enrichment of Synchronized Mouse Spermatocytes Suitable for Genome-Wide Analysis. Methods Mol Biol 2818:65-80, 2024 January, PMID: 39126467

Kurien BT, Scofield RH. Current Trends in Validating Antibody Specificities for ELISpot by Western Blotting. Methods Mol Biol 2768:15-27, 2024 January, PMID: 38502385

Chuong HH, Evatt JM, Dawson DS. Dynamic Live Cell Imaging of Budding Yeast Meiosis. Methods Mol Biol 2818:161-169, 2024 January, PMID: 39126473