What We Do
The Cardiovascular Biology Research Program investigates fundamental mechanisms involved in blood and lymphatic vessel function, atherogenesis, blood coagulation, inflammation, and sepsis.
This program utilizes a multidisciplinary approach to address these questions at a molecular level. This approach encompasses structural biology, structure-function analysis of enzymes and receptors, regulation of the relevant genes, in vivo studies using transgenic and gene deletion approaches, cell biology, protein chemistry, physiological studies, and biophysical methods for analyzing protein-protein, membrane-protein, and cell-cell interactions.
The multidisciplinary approach provides insights into processes with relevance to many human diseases, including heart attack, stroke, septic shock, cancer, and inflammatory bowel disease. Several findings by program members have generated patents and licenses that may lead to new diagnostics and therapeutics.
Member and Program Chair
Cardiovascular Biology Research Program
Oklahoma Medical Research Foundation
825 NE 13th Street, MS 45
Oklahoma City, OK 73104
Phone: (405) 271-6480
Fax: (405) 271-3137