Free Radical Biology Metabolic Regulation Journal Club 2013

	Presenter	Topic	Location
Aug. 29	Presenter: Lee Bockus Scribe: Rob Jackson Mentor: Dr. Tim Griffin	“Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor”	MC-204 4:00 PM
Sept. 5	Presenter: Rob Jackson Scribe: Lee Bockus Mentor: Dr. Ken Humphries	“Histone Acetylation Regulates Intracellular pH” McBrian, 2013 Molecular Cell http://www.sciencedirect.com/science/article /pii/S1097276512009069#	MC-204 4:00 PM
Sept. 12	Presenter: Scribe: Mentor:	NO MEETING	MC-204 4:00 PM
Sept. 19	Presenter: Clair Crewe Scribe: Yao Fu Mentor: Dr. Ann Louise Olson	“FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure”	MC-204 4:00 PM
Sept. 26	Presenter: Jami Gurley Scribe: Rachel Lane Mentor: Dr. Erika Lopes	“Maternal diet and aging alter the epigenetic control of a promoter–enhancer interaction at the Hnf4a gene in rat pancreatic islets”.	MC-204 4:00 PM
Oct. 3	Presenter: Zhaoyu Liu Scribe: Megan Brophy Mentor: Dr. Satoshi Matsuzaki	“Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1”	MC-204 4:00 PM
Oct. 10	Presenter: Megan Brophy Scribe: Clair Crewe Mentor: Dr. Tim Griffin	“Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK”	MC-204 4:00 PM
Oct. 17	Presenter: Yao Fu Scribe: Jolyn Fernandes Mentor: Dr. Ken Humphries	“The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy”	MC-204 4:00 PM
Oct. 24	Presenter: Jolyn Fernandes Scribe: Nan Zhang Mentor: Dr. Satoshi Matsuzaki	“DNMT1 Is Regulated by ATP-Citrate Lyase and Maintains Methylation Patterns during Adipocyte Differentiation”	MC-204 4:00 PM
Oct. 31	NO MEETING		MC-204 4:00 PM
Nov. 7	Presenter: Nan Zhang Scribe: Zhaoyu Liu Mentor: Dr. Ann Louise Olson	“A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use”	MC-204 4:00 PM
Nov. 14	NO MEETING		MC-204 4:00 PM
Nov. 22	Presenter: Rachel Lane Scribe: Jami Gurley Mentor:Dr. Erika Lopes	“The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation”	MC-204 4:00 PM
Nov. 28	Thanksgiving Break		MC-204 4:00 PM
Dec. 6	Semester Synthesis Meeting		MC-204 4:00 PM
Jan. 17	Introduction		MC-204 4:00 PM
Jan. 23	Presenters: Autophagy Topic Group: Rachel Lane, Rob Jackson, Jami Gurley Scribe: Mentor:	“Influence of Glucagon, an Inducer of Cellular Autophagy, on some Physical Properties of Rat Liver Lysosomes”	MC-204 4:00 PM
Jan. 30	Presenter: Jami Gurley Scribe: Mentor:	“The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress”.	MC-204 4:00 PM
Feb. 6	Presenter: Rob Jackson Scribe: Mentor:	“Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development”	MC-204 4:00 PM
Feb. 13	Presenter: Rachel Lane Scribe: Mentor:	“The Autophagy-related Gene 14 (Atg14) Is Regulated by Forkhead Box O Transcription Factors and Circadian Rhythms and Plays a Critical Role in Hepatic Autophagy and Lipid Metabolism”	MMC-204 4:00 PM
Feb. 20	Presenter: Cancer Topic Group: Clair Crewe, Megan Brophy, Yao Fu Scribe: Mentor:	“Passing Through a Tumor CO2-Combining Power of Blood Sugar, Lactic Acid, and of Tumors: II. Changes in the Carbohydrate Metabolism”	MC-204 4:00 PM
Feb. 27	Presenter: Megan Brophy Scribe: Mentor:	“Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate hehydrogenase kinase 1”	MC-204 4:00 PM
Mar. 6	Presenter: Yao Fu Scribe: Mentor:	“AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo“	MC-204 4:00 PM
Mar. 13	Presenter: Clair Crewe Scribe: Mentor:	“Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth”	MC-204 4:00 PM
Mar. 20	Spring Break		MC-204 4:00 PM
Mar. 27	OMRF Retreat		MC-204 4:00 PM
Apr. 3	Great Symposium		MC-204 4:00 PM
Apr. 10	Presenter: Thermoregulation Topic Group – Jolyn Fernandes, Nan Zhang, Lee Bockus Scribe: Mentor:	“The identification of the component in the inner membrane of brown adipose tissue mitochondria responsible for regulating energy dissipation“	MC-204 4:00 PM
Apr. 17	Presenter: Jolyn Fernandes Scribe: Mentor	“Activation of the cold-sensing TRPM8 channel triggers UCP1-dependent thermogenesis and prevents obesity”	MC-204 4:00 PM
Apr. 24	Presenter: Lee Bockus Scribe: Mentor	“Triiodothyronine induces UCP-1 expression and mitochondrial biogenesis in human adipocytes”	MC-204 4:00 PM
May 1	Presenter: Scribe: Mentor	NO MEETING	MC-204 4:00 PM
May 8	Presenter: Nan Zhang Scribe: Mentor	“Cold Exposure Promotes Atherosclerotic Plaque Growth and Instability via UCP1-Dependent Lipolysis”	MC-204 4:00 PM
			MC-204 4:00 PM
			MC-204 4:00 PM

The Free Radical Biology & Aging Metabolic Regulation Journal Club meets on Thursdays from 4:00 p.m. to 5:00 p.m. in MC-206, unless otherwise posted. To sign up for a particular date contact Tim Griffin at griffint@omrf.org or 271-7579.

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