The effect of substrates on the kinetics and the in vivo threshold activity of mutant HIV-1 proteases.
Structure of a G48H mutant of HIV-1 protease explains how glycine-48 replacements produce mutants resistant to inhibitor drugs.
Kinetic properties of saquinavir-resistant mutants of human immunodeficiency virus type 1 protease and their implications in drug resistance in vivo.
The crystal structure of bovine bile salt activated lipase: insights into the bile salt activation mechanism.
