Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen.
Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis.
Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure.
Sepsis-induced coagulation in the baboon lung is associated with decreased tissue factor pathway inhibitor.