Technology Ventures
Success Stories
Since the late 1980s, OMRF has a track record of moving discoveries from the laboratory bench to patients’ bedsides. Whether in the form of spin-off companies, diagnostic tests or therapeutics, the work of our scientists has consistently given birth to biotechnology ventures that have yielded commercial success and have made a measurable positive impact on the lives of patients.
Using OMRF technology, Equilibra Bioscience is developing a drug that could prevent or reduce the frequency of bleeding episodes in adults with severe hemophilia A and hemophilia B with or without inhibitors.
Created from an OMRF discovery, this drug from Novartis was the first targeted therapy approved for the treatment of the pain crises in sickle cell disease.
A worldwide leader in rare disease drug development and commercialization, this publicly-traded company has a market capitalization in excess of $40 billion. OMRF scientists made the seminal discovery that led to the creation of Soliris, Alexion’s first-in-class treatment for the blood disorder PNH.
Created from an OMRF discovery, this therapy from Baxter for patients with a life-threatening protein C deficiency was the first drug licensed under the European Union’s centralized marketing procedure.
This South San Francisco-based biotech company develops drugs for the treatment of central nervous system diseases. Formed based on OMRF technology for the treatment of Alzheimer’s disease, CoMentis’ investors include Sanderling Ventures, Clarus Ventures and Astellas Pharma.
A molecular diagnostics company, Crescendo is founded on OMRF technology that measures disease activity and treatment response in rheumatoid arthritis patients. After developing Vectra DA, an advanced blood test that measures disease activity and is used by rheumatologists and patients everywhere, the company was acquired by Myriad Genetics for $270 million.
This nutraceutical company has created a topical cream for treatment of skin conditions like dermatitis and eczema.
Using OMRF technology, InterGenetics developed a test to predict a woman’s lifetime risk of developing breast cancer.
The product of joint research from OMRF and the Hough Ear Institute, Otologic is forging innovative approaches to prevent and treat hearing loss.
Progentec is developing cytokine biomarker-based tests for more accurate diagnosis, measurement of disease activity, and prediction of flares in patients with lupus.
Q BioMed, Inc. is a biotech acceleration and commercial stage company licensing Uttroside-B technology, and pursuing it as a new treatment of liver cancer. Uttroside-B is the product of joint research between OMRF and Rajiv Gandhi Centre for Biotechnology.
After building on OMRF discoveries to create an investigational new drug to treat ischemic stroke, Renovis was acquired by Evotec AG.
This biotechnology company developed an experimental drug for sickle cell disease based on discoveries made at OMRF. Novartis subsequently acquired Selexys in a deal valued at up to $665 million.
Utilizing OMRF technology, this clinical-stage biopharmaceutical company has created an experimental drug to enhance the efficacy of hematopoietic stem cell transplants derived from cord blood.
This Israeli company was building on OMRF technology to establish therapeutics for neurodegenerative disorders like Alzheimer’s and Batten disease. Xonovo was a portfolio company in the biotech accelerator FutuRx, which was backed by venture arms of Johnson & Johnson, Takeda and OrbiMed.
