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Home - Findings - Long Live the Grant!

Long Live the Grant!

When a scientist receives a grant, that’s great news. The funding provides the means for a scientist to explore a hypothesis and run his or her lab. But those grants are not unlimited; they provide funding only for a set period of time, typically three to five years. But for OMRF’s Dr. Paul Kincade, one grant has proven the medical research equivalent of the Energizer Bunny.

First awarded to Kincade when Richard Nixon was President and bell bottoms were the rage, Early events in mammalian B-cell differentiation has remained funded for a whopping 38 years. Kincade attributes this success, which includes seven separate renewals of the grant, to hard work, a steady stream of new findings and, of course, a little bit of luck. Still, after almost 40 years, does anything remain to be learned about this particular topic?

“The human immune system is an incredibly intricate machine, and every day we learn something new about how it develops and functions,” says Kincade, who holds the William H. and Rita Bell Chair in Biomedical Research at OMRF.  “That knowledge continues to help us better understand and treat diseases like lupus, leukemias and lymphomas.”

 

Grants Awarded

January – June, 2012

Dr. José Alberola-Ila

Hematopoietic stem cell senescence

Dr. Yunzhou Dong

Role of epsins in atherosclerosis; Drug development for prostate cancer

Dr. Michael Dresser

Zeiss LSM710 confocal fluorescence microscope for live stem-cell imaging; Mechanics and regulation of chromosome dynamics in meiotic prophase

Dr. Taishan Hu

RAS/MAPK cascade controls iNKT cell development and function

Dr. Kenneth Humphries

Mitochondrial dysfunction in amyotrophic lateral sclerosis

Dr. Judith A. James

Oklahoma Autoimmunity Center for Excellence

Dr. Paul W. Kincade

Hematopoietic stem cell senescence; Early events in mammalian B-cell differentiation

Dr. Hui-Ying Lim

A fluorescence stereomicroscope for characterization of adult stem cells in intact tissues of various model systems

Dr. Florea Lupu

Spinning disk confocal microscope for intravital imaging; Complement inhibition as sepsis therapy

Dr. Rodger P. McEver

Interdisciplinary research in vascular biology; Cellular regulation of selectin-ligand interactions; Mechanisms for blood cell adhesion under flow; Protein-glycan interactions in the vascular system

Dr. Joan Merrill

Clinical outcomes and quality of life of lupus nephritis patients in a prospective international inception cohort

Dr. Kenneth G. Miller

Signaling pathways that regulate synaptic transmission

Dr. Courtney Montgomery

Comprehensive genome interrogation of African-American sarcoidosis families

Dr. Swapan K. Nath

SLE susceptibility and clinical significance at 2q22-24 across multiple ethnicities; Identification of lupus predisposing variants by comparing multiple populations

Dr. Xiao-Hong Sun

Notch-induced protein degradation in lymphopoiesis

Dr. Linda Thompson

Fluorescence activated cell sorters upgrade

Dr. Weidong Wang

An automated high-throughput microscope for adult stem cell research in Oklahoma

Dr. Lijun Xia

Role of mucin-type O-glycans in intestinal inflammation; Microtome for histological analysis of adult stem cell based therapies

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