Human hypofunctional NCF1 variants promote pulmonary fibrosis in the bleomycin-induced mouse model and patients with systemic sclerosis via expansion of SPP1(+) monocytes-derived macrophages.
Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females.
Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland.
A genome-wide association study suggests new susceptibility loci for primary antiphospholipid syndrome.
Association of autoantibody concentrations and trajectories with lupus nephritis histological features and treatment response.
