Gnotobiotic Mouse Core About Gnotobiotic (germfree, defined colonized) rodents have become powerful tools to advance our understanding of the host–microbiome relationship. However, the maintenance and ultimately the monitoring of gnotobiotic rodents is a critical, labor-intensive, and costly process (e.g., sterility, not absence of specific pathogens, must be demonstrated in germfree animals). The necessary gnotobiology techniques […]
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