| Sept 14 | Intro to FRBA labs by PIs | (2:30-4:30pm) |
| Sept 21 | No Seminar | FRBA Annual Retreat |
| Sept 28 | Dr. Prescott | ”From one mistake to another” |
| Oct 5 | No Seminar | |
| Oct 12 | No Seminar | OU Fall Break – OU/Texas Football |
| Oct 19 | Mike/Sunji | ”The discovery of superoxide dismutase by McCord and Fridovich”/”Characterization of eye-specific genes in Drosophila phototransduction” |
| Oct 26 | Chelsea/Rachel | “Expression profiling and functional analysis of UbcM2 in the central nervous system”/”Distinguishing the metabolic contribution of gender and BMI to osteoarthritis disease pathology”Luke |
| Nov 2 | Gary/Clair | “Probing the response of the mitochondrial network to proteotoxic stress”/”The adaptive cardiac response to high-dietary fat: regulation of pyruvate dehydrogenase for appropriate pyruvate handling”Tim |
| Nov 9 | PIs to discuss retreat | Mike |
| Nov 16 | Jolyn/Yao | “Enhanced Cardiac Fatty Acid Utilization leads to Aconitase Stability in Response to High Dietary Fat”/“The role of mitochondrial antioxidant Sod2 in aging-associated osteoarthritis”Ken |
| Nov 23 | No Seminar | Thanksgiving |
| Nov 30 | Aaron/Satoshi | “Glutathionylation of alpha-ketoglutarate dehydrogenase: the chemical nature and relative susceptibility of the cofactor lipoic acid to modification”/”Ischemia-mediated changes in Complex I activity – a cellular approach”Hui-Ying |
| Dec 7 | Paul/Lee | “Give it some gas! Energetic substrate octane, mitochondrial redox exhaust, and cardiac metabolism”/”Chronic adrenergic stimulation and oxidation cause the degradation of protein kinase A (PKA) in the diabetic heart”/Scott |
| Dec 14 | Tim G./Ken H. | CANCELLED |
| Dec 21 | No Seminar | Christmas |
| Dec 28 | No Seminar | New Year’s |
| Jan 11 | Max Weitzenhoffer | “50 years in the theatre — a half century of change”/Luke Szweda, Ph.D. |
| Jan 18 | Dr. Steven C. Agee | “The serendipitous nature of a working career”/Scott Plafker, Ph.D. |
| Jan 25 | OMRF RETREAT | |
| Feb 1 | Clair Crewe/Yao Fu | “Diurnal Regulation of Pyruvate Dehydrogenase Kinase 4: Uncovering New Mechanisms for Regulation of Mitochondrial Substrate Selection” / “Age-Dependent Increase in Sod2 Acetylation and Nitration in Cartilage” |
| Feb 8 | Hui-Ying Lim | “Intercellular ROS Signaling in Fish and Frogs: How Flies Could Be Different” |
| Feb 15 | Tim Griffin/Ken Humphries | “Is There a Metabolic Basis to Osteoarthritis? If I’m a Betting Man, I Like the Odds.”/”Redox Regulation of Cardiac Function: PKA and Beyond” |
| Feb 22 | Gary O’Mealey/ Jolyn Fernandes | “Nrf2 Regulates the Mitochondrial Response to Proteotoxic Stress”/”Role of Mitochondrial Aconitase in Cardiac Metabolic Changes Induced by High Dietary Fiber” |
| Mar 1 | NO SEMINAR | |
| Mar 7 | Alexander M. van der Bliek, Ph.D./Scott | “Mitochondrial Fission, Fusion and Stress” |
| Mar 15 | Lee Bockus | “Oxidative and proteasomal regulation of protein kinase A” |
| Mar 21 | P. Darrell Neufer, Ph.D./Luke | “Bioenergetics, Redox Biology and Insulin Sensitivity” |
| Apr 5 | Paul Rindler, Ph.D. / Satoshi Matsuzaki, Ph.D. | “Is it Crazy to Think that High Fat Diet-Induced Insulin Resistance in Muscle Promotes Alzheimer Disease?” / “OH” |
| Apr 12 | Sunji Lee / | “Genetic Screen for Genes Involved in High-Fat Diet-Induced Obesity and Heart Dysfunction” |
| Apr 19 | NO SEMINAR | |
| Apr 26 | Dr. Joseph Garcia / Luke | Joseph A. Garcia, MD, PhD; UT Southwestern - “HIF-2: Crucial Regulator of the Mammalian Stress Response” |
| May 3 | Rachel Lane / Chelsea Larabee | “Mechanisms Mitochondrial Function in Osteoarthritis: Effect of Increased Oxidative Phosphorylation on Chondrocyte Oxidative Homeostasis” / “Exploring the Regulation of Nrf2 in Multiple Sclerosis” |
| May 9 | Robert Terkeltabaub, MD; Interim Chief, Div of Rheum Allergy & Immuno, Prof of Med, Univ of CA at San Diego | “Interfaces Between Inflammation and Skeletal Biology” |
| May 10 | Aaron McLain | “Redox Regulation of alpha-Ketoglutarate Dehydrogenase by Reversible Glutathionylation” |
| May 17 | GAME DAY | |
| May 31 | Luke Szweda | “State of FRB&A Address” |
The Free Radical Biology & Aging Research Seminar Series will begin in October. Unless otherwise noted, seminars are held Friday afternoons from 3:30 p.m. to 4:30 p.m. in MC-206. If you would like to be on the mailing list for this seminar series, send e-mail to evansj@omrf.org. Free Radical Biology Research Seminar Series 2010 – 2011
