The Immunobiology and Cancer Research Program, led by Paul W. Kincade, Ph.D., is principally concerned with understanding the normal development and function of cells in the immune system. We hope this research will, in turn, help shed light on disease, as abnormalities in these processes result in leukemia, lymphomas and immunodeficiency diseases. Although astonishing progress has been made, we have much to learn if we are truly to conquer these conditions.

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2012

Blackburn MR, Thompson LF. Adenosine deaminase deficiency: unanticipated benefits from the study of a rare immunodeficiency. J Immunol 188:933-935, 2012. [Abstract]

* Ichii M, Frank MB, Iozzo RV, Kincade PW. The canonical Wnt pathway shapes niches supportive for hematopoietic stem/progenitor cells. Blood 2012. [Abstract] EPub

Luis TC, Ichii M, Brugman MH, Kincade P, Staal FJ. Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development. Leukemia 2012. [Abstract] EPub

Rose K, Long P, Shankar M, Ballard JD, Webb CF. Serum amyloid A protects murine macrophages from lethal toxin-mediated death. Cell Immunol 272:175-181, 2012. [Abstract]

Takedachi M, Oohara H, Smith BJ, Iyama M, Kobashi M, Maeda K, Long CL, Humphrey MB, Stoecker BJ, Toyosawa S, Thompson LF, Murakami S. CD73-generated adenosine promotes osteoblast differentiation. J Cell Physiol 2012. [Abstract] EPub

Tsukamoto H, Chernogorova P, Ayata K, Gerlach UV, Rughani A, Ritchey JW, Ganesan J, Follo M, Zeiser R, Thompson LF, Idzko M. Deficiency of CD73/ecto-5′-nucleotidase in mice enhances acute graft-versus-host disease. Blood 2012. [Abstract] EPub

* Vista E, Crowe S, Thompson L, Air G, Robertson J, Guthridge J, James J. Influenza vaccination can induce new-onset anticardiolipins but not beta2-glycoprotein-I antibodies among patients with systemic lupus erythematosus. Lupus 21:168-174, 2012. [Abstract]

Wu W, Sun XH. Janus kinase 3: the controller and the controlled. Acta Biochim Biophys Sin (Shanghai) 2012. [Abstract] EPub

Zhang Q, Iida R, Shimazu T, Kincade PW. Replenishing B lymphocytes in health and disease. Curr Opin Immunol 2012. [Abstract] EPub

* Indicates publications by more than one department.

Immunobiology & Cancer Research Program
Oklahoma Medical Research Foundation
825 NE 13th Street, MS 23
Oklahoma City, OK 73104

Phone: (405) 271-7905
Fax: (405) 271-8568
Email: kincade@omrf.org