The Immunobiology and Cancer Research Program, led by Paul W. Kincade, Ph.D., is principally concerned with understanding the normal development and function of cells in the immune system. We hope this research will, in turn, help shed light on disease, as abnormalities in these processes result in leukemia, lymphomas and immunodeficiency diseases. Although astonishing progress has been made, we have much to learn if we are truly to conquer these conditions.

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2012

Blackburn MR, Thompson LF. Adenosine deaminase deficiency: unanticipated benefits from the study of a rare immunodeficiency. J Immunol 188:933-935, 2012. [Abstract]

* Ichii M, Frank MB, Iozzo RV, Kincade PW. The canonical Wnt pathway shapes niches supportive for hematopoietic stem/progenitor cells. Blood 119:1683-1692, 2012.  [Abstract]

Luis TC, Ichii M, Brugman MH, Kincade P, Staal FJ. Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development. Leukemia 26:414-421, 2012. [Abstract]

Rose K, Long P, Shankar M, Ballard JD, Webb CF. Serum amyloid A protects murine macrophages from lethal toxin-mediated death. Cell Immunol 272:175-181, 2012. [Abstract]

Shimazu T, Iida R, Zhang Q, Welner RS, Medina KL, Alberola-Ila J, Kincade PW. CD86 is expressed on murine hematopoietic stem cells and denotes lymphopoietic potential. Blood 2012. [Abstract] EPub

Takedachi M, Oohara H, Smith BJ, Iyama M, Kobashi M, Maeda K, Long CL, Humphrey MB, Stoecker BJ, Toyosawa S, Thompson LF, Murakami S. CD73-generated adenosine promotes osteoblast differentiation. J Cell Physiol 227:2622-2631, 2012.    [Abstract]

Tsukamoto H, Chernogorova P, Ayata K, Gerlach UV, Rughani A, Ritchey JW, Ganesan J, Follo M, Zeiser R, Thompson LF, Idzko M. Deficiency of CD73/ecto-5′-nucleotidase in mice enhances acute graft-versus-host disease. Blood 2012. [Abstract] EPub

* Vista E, Crowe S, Thompson L, Air G, Robertson J, Guthridge J, James J. Influenza vaccination can induce new-onset anticardiolipins but not beta2-glycoprotein-I antibodies among patients with systemic lupus erythematosus. Lupus 21:168-174, 2012. [Abstract]

Wang HC, Peng V, Zhao Y, Sun XH. Enhanced notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic mice. PLoS One 7:e32944, 2012. [Abstract] EPub

Wu W, Sun XH. Janus kinase 3: the controller and the controlled. Acta Biochim Biophys Sin (Shanghai) 44:187-196, 2012.[Abstract]

Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli M, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperriere D, Leprince D, de CT, Prince KL, Putker M, Del PL, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van RC, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O’Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner N, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, Lebrun DP, Biswal S, Harvey CJ, Debruyne JP, Hogenesch JB, Hevner RF, Heligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW. The Transcription Factor Encyclopedia. Genome Biol 13:R24, 2012. [Abstract] EPub

Zhang Q, Iida R, Shimazu T, Kincade PW. Replenishing B lymphocytes in health and disease. Curr Opin Immunol 2012. [Abstract] EPub

* Indicates publications by more than one department.

Immunobiology & Cancer Research Program
Oklahoma Medical Research Foundation
825 NE 13th Street, MS 23
Oklahoma City, OK 73104

Phone: (405) 271-7905
Fax: (405) 271-8568
Email: kincade@omrf.org