Research in this program focuses on using model organisms to address complex molecular and cell biological questions; such questions are often impossible to investigate directly using human cell lines or mammalian animal models. Each investigator in this program specializes in using a model organism, such as E. coli (bacteria), Dictyostelium (a slime mold), and C. elegans (a roundworm), to address important questions applicable to human biology and disease. Rather than being focused on a single disease, the laboratories in this program are united by a common way of thinking about biological problems and a shared interest in using model organisms.

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Mesa R, Luo S, Hoover CM, Miller K, Minniti A, Inestrosa N, Nonet ML. HID-1, a new component of the peptidergic signaling pathway. Genetics 187:467-483, 2011. [Abstract]

* Indicates publications by more than one department.

Genetic Models of Disease Research Program
Oklahoma Medical Research Foundation
825 NE 13th Street, MS 48
Oklahoma City, OK 73104

Phone: (405) 271-7660
Fax: (405) 271-7312
Email: heather-hope@omrf.org