What We Do

coagulationbio frontpage1 Coagulation Biology Laboratory

The Coagulation Biology Laboratory, headed by Charles T. Esmon, Ph.D., investigates the fundamental mechanisms involved in blood coagulation, including complex biological processes such as inflammation, cancer and cardiovascular disease.

   [MORE]

Our Publications

coagulationbio frontpage1 Coagulation Biology Laboratory

2012

Cohen MJ, Call M, Nelson M, Calfee CS, Esmon CT, Brohi K, Pittet JF. Critical role of Activated Protein C in early coagulopathy and later organ failure, infection and death in trauma patients. Ann Surg 255:379-385,2012. [Abstract]

Esmon CT. Protein C anticoagulant system–anti-inflammatory effects. Semin Immunopathol 34:127-132, 2012. [Abstract]

* Izmirly PM, Shvartsbeyn M, Meehan S, Franks A, Braun A, Ginzler E, Xu SX, Yee H, Rivera T, Esmon C, Barisoni L, Merrill JT, Buyon JP, Clancy RM. Dysregulation of the microvasculature in nonlesional non-sun-exposed skin of patients with lupus nephritis. J Rheumatol 2012. [Abstract] EPub

Lopez-Sagaseta J, Puy C, Tamayo I, Allende M, Cervero J, Velasco SE, Esmon CT, Montes R, Hermida J. sPLA2-V inhibits EPCR anticoagulant and antiapoptotic properties by accommodating lysophosphatidylcholine or PAF in the hydrophobic groove. Blood 2012. [Abstract] EPub

Madhusudhan T, Wang H, Straub BK, Grone E, Zhou Q, Shahzad K, Muller-Krebs S, Schwenger V, Gerlitz B, Grinnell BW, Griffin JH, Reiser J, Grone HJ, Esmon CT, Nawroth PP, Isermann B. Cytoprotective signaling by activated protein C requires protease- activated receptor-3 in podocytes. Blood 119:873-882 2012. [Abstract]

* indicates publications by more than one department

Contact Us

coagulationbio frontpage1 Coagulation Biology Laboratory

Coagulation Biology Laboratory, MS 51
Oklahoma Medical Research Foundation
825 N.E. 13th Street
Oklahoma City, OK 73104

Phone: (405) 271-6474
Fax: (405) 271-2870
E-mail: esmonc@omrf.org