Genetic Models of Disease Research Program

Research in this program focuses on using model organisms to address complex molecular and cell biological questions; such questions are often impossible to investigate directly using human cell lines or mammalian animal models. Each investigator in this program specializes in using a model organism, such as E. coli (bacteria), Dictyostelium (a slime mold), and C. elegans (a roundworm), to address important questions applicable to human biology and disease. Rather than being focused on a single disease, the laboratories in this program are united by a common way of thinking about biological problems and a shared interest in using model organisms.

2012

Mathews EA, Mullen GP, Hodgkin J, Duerr JS, Rand JB. Genetic Interactions between UNC-17/VAChT and a Novel Transmembrane Protein in Caenorhabditis elegans. Genetics 192:1315-1325,2012. [Abstract]

Mullen GP, Grundahl KM, Gu M, Watanabe S, Hobson RJ, Crowell JA, McManus JR, Mathews EA, Jorgensen EM, Rand JB. UNC-41/Stonin functions with AP2 to recycle synaptic vesicles in Caenorhabditis elegans. PLoS One 7:e40095, 2012. [Abstract]

2013

Edwards SL, Yu SC, Hoover CM, Phillips BC, Richmond JE, Miller KG. An Organelle Gatekeeper Function for Caenorhabditis elegans UNC-16 (JIP3) at the Axon Initial Segment. Genetics 194:143-161, 2013. [Abstract]
* Indicates publications by more than one department.

Genetic Models of Disease Research Program
Oklahoma Medical Research Foundation
825 NE 13th Street, MS 48
Oklahoma City, OK 73104

Phone: (405) 271-7660
Fax: (405) 271-7312
Email: heather-hope@omrf.org