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Genetic Models of Disease Laboratory

       What We Do

Research in this laboratory uses the model organism C. elegans (a roundworm) to address complex molecular and cell biological questions that are often impossible to investigate directly using human cell lines or mammalian animal models. Rather than being focused on a single disease, the laboratory relies on a common way of thinking about biological problems and an interest in using model organisms as a way to understand human biology.

       Our Scientists

       Our Publications


Mathews EA, Mullen GP, Manjarrez JR, Rand JB. Unusual regulation of splicing of the cholinergic locus in Caenorhabditis elegans. Genetics 199:729-737, 2015. [Abstract]


Hoover CM, Edwards SL, Yu SC, Kittelmann M, Richmond JE, Eimer S, Yorks RM, Miller KG. A Novel CaM Kinase II Pathway Controls the Location of Neuropeptide Release from Caenorhabditis elegans Motor Neurons. Genetics 196:745-765, 2014. [Abstract]

       Contact Us

Genetic Models of Disease Research Program
Oklahoma Medical Research Foundation
825 NE 13th Street, MS 48
Oklahoma City, OK 73104

Phone: (405) 271-8168
Fax: (405) 271-7312