Coagulation Biology Laboratory

2013

Bock F, Shahzad K, Wang H, Stoyanov S, Wolter J, Dong W, Pelicci PG, Kashif M, Ranjan S, Schmidt S, Ritzel R, Schwenger V, Reymann KG, Esmon CT, Madhusudhan T, Nawroth PP, Isermann B. Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc. Proc Natl Acad Sci U S A 110:648-653, 2013. [Abstract]

Borissoff JI, Otten JJ, Heeneman S, Leenders P, van Oerle R., Soehnlein O, Loubele ST, Hamulyak K, Hackeng TM, Daemen MJ, Degen JL, Weiler H, Esmon CT, van Ryn J., Biessen EA, Spronk HM, Ten Cate H. Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner. PLoS One 8:e55784, 2013. [Abstract]

Esmon CT. Molecular circuits in thrombosis and inflammation. Thromb Haemost 109:416-420, 2013. [Abstract]

Kager LM, Wiersinga WJ, Roelofs JJ, Meijers JC, Zeerleder SS, Esmon CT, Van't Veer C, van der Poll T. Endogenous protein C has a protective role during gram-negative pneumosepsis (melioidosis). J Thromb Haemost 11:282-292,2013. [Abstract]

Kager LM, Roelofs JJ, de Vos AF, Wieland CW, Schouten M, Meijers JC, Isermann B, Van't Veer C, Esmon CT, van der Poll T. The endothelial protein C receptor and activated protein C play a limited role in host defense during experimental tuberculosis. Thromb Haemost 109: 726-737,2013. [Abstract]

Nayak RC, Keshava S, Esmon CT, Pendurthi UR, Rao LV. Rab GTPases Regulate Endothelial Cell Protein C Receptor-Mediated Endocytosis and Trafficking of Factor VIIa. PLoS One 8:e59304, 2013. [Abstract]

Schaffner F, Yokota N, Carneiro-Lobo T, Kitano M, Schaffer M, Anderson GM, Mueller BM, Esmon CT, Ruf W. Endothelial Protein C Receptor Function in Murine and Human Breast Cancer Development. PLoS One 8:e61071, 2013. [Abstract]

Vadivel K, Agah S, Messer AS, Cascio D, Bajaj MS, Krishnaswamy S, Esmon CT, Padmanabhan K, Bajaj SP. Structural and Functional Studies of gamma-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium. J Mol Biol 425:1961-1981,2013. [Abstract]