What We Do
The Advanced Magnetic Resonance Center is shared by researchers at the Oklahoma Medical Research Foundation (OMRF) and the University of Oklahoma Health Sciences Center (OUHSC) primarily as well as other researchers in Oklahoma. Our biomedical research interests include, but are not limited to, cancer biology, neurological disorders and cardiovascular pathologies.
Our research target themes are addressed with techniques such as basic morphological MRI (e.g. T1, T2 imaging), dynamic contrast-enhanced MRI (DCE) to establish location and extent of pathological lesions, MR angiography (MRA) to visualize vascularization, functional MRI (fMRI) to monitor tissue/organ response given a challenge function, and MR spectroscopy (MRS) to follow metabolic changes during a disease processes.
Advanced Magnetic Resonance Center
Seong J, Jeong W, Smith N, Towner RA. Hemodynamic effects of long-term morphological changes in the human carotid sinus. J Biomech 2015. [Abstract] EPub
Towner RA, Smith N, Saunders D, Van Gordon SB, Wisniewski AB, Tyler KR, Greenwood-Van MB, Hurst RE. Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI) as a diagnostic tool for assessing bladder permeability and associated colon cross-talk: pre-clinical studies in a rat model. J Urol 2015. [Abstract] EPub
Gomez-Mejiba SE, Zhai Z, Della-Vedova MC, Munoz MD, Chatterjee S, Towner RA, Hensley K, Floyd RA, Mason RP, Ramirez DC. Immuno-spin trapping from biochemistry to medicine: Advances, challenges, and pitfalls. Focus on protein-centered radicals. Biochim Biophys Acta 1840:722-729, 2014. [Abstract]
Towner RA, Smith N, Saunders D, Van Gordon SB, Wisniewski AB, Tyler KR, Greenwood-Van MB, Hurst RE. Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI) as a diagnostic tool for assessing bladder permeability and associated colon cross-talk: pre-clinical studies in a rat model. J Urol 2014. [Abstract] EPub
* Towner RA, Wren JD. Prioritizing uncharacterized genes in the search for glioma biomarkers. CNS Oncol 3:93-95, 2014. [Abstract]
* Zhao Y, Ling F, Griffin TM, He T, Towner R, Ruan H, Sun XH. Up-regulation of the Sirt1 and PCG-1alpha genes in white adipose tissue of Id1 deficient mice: implications in the protection against diet and age-induced glucose intolerance. J Biol Chem 289:29112-29122, 2014. [Abstract]
Advanced Magnetic Resonance Center, MS 60
Oklahoma Medical Research Foundation
825 NE 13th Street
Oklahoma City, OK 73104
Phone: (405) 271-7232
Fax: (405) 271-7254