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Advanced Magnetic Resonance Center

       What We Do

The Advanced Magnetic Resonance Center is shared by researchers at the Oklahoma Medical Research Foundation (OMRF) and the University of Oklahoma Health Sciences Center (OUHSC) primarily as well as other researchers in Oklahoma. Our biomedical research interests include, but are not limited to, cancer biology, neurological disorders and cardiovascular pathologies.

Our research target themes are addressed with techniques such as basic morphological MRI (e.g. T1, T2 imaging), dynamic contrast-enhanced MRI (DCE) to establish location and extent of pathological lesions, MR angiography (MRA) to visualize vascularization, functional MRI (fMRI) to monitor tissue/organ response given a challenge function, and MR spectroscopy (MRS) to follow metabolic changes during a disease processes.

       Our Publications

Advanced Magnetic Resonance Center

2013

* Floyd RA, Castro Faria Neto HC, Zimmerman GA, Hensley K, Towner RA. Nitrone-based Therapeutics for Neurodegenerative Diseases. Their use alone or in Combination with Lanthionines. Free Radic Biol Med  62:145-156,2013. [Abstract]

* Garteiser P, Doblas S, Towner RA, Griffin TM. Calibration of a semi-automated segmenting method for quantification of adipose tissue compartments from magnetic resonance images of mice. Metabolism  62:1686-1695, 2013. [Abstract]

* He T, Smith N, Saunders D, Pittman BP, Lerner M, Lightfoot S, Silasi-Mansat R, Lupu F, Towner RA. Molecular MRI differentiation of VEGF receptor-2 levels in C6 and RG2 glioma models. Am J Nucl Med Mol Imaging 3:300-311, 2013. [Abstract]

Piao D, Towner RA, Smith N, Chen WR. Magnetothermoacoustics from magnetic nanoparticles by short bursting or frequency chirped alternating magnetic field: A theoretical feasibility analysis. Med Phys 40:063301, 2013. [Abstract]

* Towner RA, Garteiser P, Bozza F, Smith N, Saunders D, d'Avila JC, Magno F, Oliveira MF, Ehrenshaft M, Lupu F, Silasi-Mansat R, Ramirez DC, Gomez-Mejiba SE, Mason RP, Faria-Neto HC. In Vivo Detection of Free Radicals in Mouse Septic Encephalopathy using Molecular MRI and Immuno-Spin-Trapping. Free Radic Biol Med 65C:828-837, 2013. [Abstract]

* Towner RA, Gillespie DL, Schwager A, Saunders DG, Smith N, Njoku CE, Krysiak RS, III, Larabee C, Iqbal H, Floyd RA, Bourne DW, Abdullah O, Hsu EW, Jensen RL. Regression of glioma tumor growth in F98 and U87 rat glioma models by the Nitrone OKN-007. Neuro Oncol 15:330-340, 2013. [Abstract]

* Towner RA, Jensen RL, Colman H, Vaillant B, Smith N, Casteel R, Saunders D, Gillespie DL, Silasi-Mansat R, Lupu F, Giles CB, Wren JD. ELTD1, A Potential new biomarker for gliomas. Neurosurgery 72:77-791, 2013. [Abstract]

* Towner RA, Jensen RL, Vaillant B, Colman H, Saunders D, Giles CB, Wren JD. Experimental validation of 5 in-silico predicted glioma biomarkers. Neuro Oncol 15:1625-1634,2013. [Abstract]

* Towner RA, Smith N, Saunders D, De Souza PC, Henry L, Lupu F, Silasi-Mansat R, Ehrenshaft M, Mason RP, Gomez-Mejiba SE, Ramirez DC. Combined Molecular MRI and Immuno-Spin-Trapping for in vivo Detection of Free Radicals in Orthotopic Mouse GL261 Gliomas. Biochim Biophys Acta  1832:2153-2161,2013. [Abstract]

* Towner RA, Smith N, Saunders D, Lupu F, Silasi-Mansat R, West M, Ramirez DC, Gomez-Mejiba SE, Bonini MG, Mason RP, Ehrenshaft M, Hensley K. In Vivo Detection of Free Radicals using Molecular MRI and Immuno-Spin-Trapping in a Mouse Models for Amyotrophic Lateral Sclerosis (ALS). Free Radic Biol Med 63:351-360, 2013. [Abstract]

2014

Gomez-Mejiba SE, Zhai Z, Della-Vedova MC, Munoz MD, Chatterjee S, Towner RA, Hensley K, Floyd RA, Mason RP, Ramirez DC. Immuno-spin trapping from biochemistry to medicine: Advances, challenges, and pitfalls. Focus on protein-centered radicals. Biochim Biophys Acta 1840:722-729, 2014. [Abstract]
* publications by more than one department or program

       Contact Us

Advanced Magnetic Resonance Center, MS 60
Oklahoma Medical Research Foundation
825 NE 13th Street
Oklahoma City, OK 73104

Phone: (405) 271-7232
Fax: (405) 271-7254
Email: Debra-Saunders@omrf.org